The stereocontrolled total synthesis of the C31 apocarotenoid paracentrone was achieved by sequential cross-coupling reactions using C5 boronic acid ester and iodo-substituted dienes, which were newly developed building blocks for elongation of the conjugated polyene systems at both their terminals.

In order to enhance the customer experience, it is important not only to provide functions, but also to respond to changes in environments and requirements. It is a difficult task to evaluate and manage which function with different locations and contents is most valuable to the user's experience without using computationally time-consuming optimization calculations. To address this, this paper is focusing on self-adaptive software technology. The authors built a software adaptation mechanism that can be immediately calculated online using a performance characteristic map and threshold judgment with a learning function and sequential updates. The results confirmed the effectiveness of the mechanism in an application that supports personnel exchange events.