The aim of the study was to determine influence of intellectually disability (ID) on oral hygiene status (OHS), periodontal status (PS), and periodontal treatment needs (PTNs) and investigate the association of these clinical parameters with various sociodemographic and clinical variables among multicentric institutionalized ID subjects aged 5–55 years in Kolhapur district, Maharashtra, India. This descriptive cross-sectional study was conducted by both questionnaire and clinical examination. OHS, PS, and PTNs of these subjects were assessed by recording Simplified Oral Hygiene Index (OHI-S) and Community Periodontal Index of Treatment Needs, respectively. Analysis of variance and multiple logistic and stepwise linear regression analysis were used for statistical analysis. Of the 576 subjects examined, the mean age of the subjects was 17.50 ± 7.4 years. Subjects with profound level of ID had the highest mean OHI-S, PS, and PTNs scores of 4.47 ± 1.04, 2.84 ± 0.78, and 2.25 ± 0.44, respectively, as compared with other ID groups (P<0.0001). The present study signified that ID subjects had poor OHS and PS with the highest PTNs and were influenced by age (P<0.0001), degree of ID (P<0.0001), SES, location, institution type, and parent’s level education. The present study underlines a considerable need for prevention and treatment of periodontal disease among ID subjects in India.

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Introduction: Dental implants form the mainstay of dental treatment involving rehabilitation of missing teeth. One of the major concerns for the clinicians doing dental implants is the postsurgical failure of dental implants. Success of dental implants is dependent upon the skills of the surgeon and the amount and quality of the bone remaining at the edentulous area where dental implant has to be placed. Myeloperoxidase (MPO) and nitrites are few of the enzymes and molecules which are said to be altered in inflammation. However, their exact role in the inflammatory processes around natural tooth and dental implant is still unclear. Hence we comparatively evaluated the levels of MPO and nitrites in the areas around the dental implants and natural teeth. Materials and methods: The present study comprises 42 patients who underwent prosthetic rehabilitation by dental implants from 2011 to 2014. Depth of probing value (DP), score

In the past one and half year elapsed since the identification of the SARS-CoV-2 virus and its genome, an extraordinary effort by the scientific community has led to the development of many vaccine projects. More than ten vaccine candidates throughout the world have been granted approval for emergency use. Existing data suggest that these vaccines have the potential to protect individuals and curb the spread of COVID-19 pandemic. However, long term side-effects and certain unresolved issues associated with vaccine use need to be assessed as the time passes. This study reviews the most recent data of 12 vaccines which have been approved for use and presents information on their doses, composition, mechanism of action, side effects, etc.