Aiming at the application of Sub‐6 GHz band, this paper presents a high isolation four‐port MIMO slot antenna with CPW feeding mode. About this antenna, two parallel binary antennas are oppositely arranged with connected ground, and isolation branches are adopted to improve isolation. Each element antenna is realized through elliptical shape patch and trident structure feed line. The measured results show that its working frequency band is 1.82–6.5 GHz band, with ports isolation less than −20 dB. In addition, its other performance parameters are good, such as gain of 7.03 dB and ECC parameter below 0.004, and CCL is less than 0.3 bps/Hz. The antenna has high isolation and it can not only work in the mobile communication frequency bands such as n41, n77, n78, and n79, but also work in the frequency band of the IoT, such as WiFi5, V2X, and DSRC.