Objectives: This study is designed to investigate the difference of gender, triggering factors and Heart rate variability(HRV) between left and right hemifacial spasm patients.Methods: Among hemifacial spasm patients who visited the Acupuncture and Moxibustion medicine clinic of Kyung Hee University Korean Medicine Hospital from January 1, 2017, to April 18, 2022, we reviewed the clinical records of subjects with right hemifacial spasm(n=55) and left hemifacial spasm(n=76). We investigated the difference of gender, triggering factors and HRV between left and right hemifacial spasm patients groups by student’s t-test, chi-square test and fisher's exact test using SPSS for windows(version 28.0.0.0.).Results: There was no difference in gender, triggering factors and HRV between left and right hemifacial spasm groups.Conclusion: According to this study, there were few specificity of lesions of left and right in hemifacial spasms.

Background: This study was conducted to determine the anti-inflammatory effect of astaxanthin, on atopic dermatitis.Methods: Changes in mouse body weight, lymph node weight, and the degree of improvement in symptoms were measured to determine the inflammatory response. Real-time reverse transcription-polymerase chain reaction tests were performed to determine the degree of expression of inflammation-related cytokines (IL-31 and IL-33 and chemokines such as CCL17 and CCL22), and western blot analysis was performed to evaluate the expression of inflammation-related factors (iNOS, COX-2, and NF-kB signaling molecules p-IkBα, p50, p-65 and pSTAT3).Results: The degree of symptoms significantly improved in the PA+AX group. Lymph node weight in the PA+AX group was lower than the PA group. Inflammatory cytokines (IL-31, IL-33, and inflammatory chemokines such as CCL17 and CCL22) were significantly reduced in the PA+AX group compared with the PA group. The expression of inflammatory genes (iNOS, COX-2, NF-kB and signaling molecules (p-IkBα, p50, p65, and p-STAT 3) was lower in the PA+AX group compared with the PA group.Conclusion: Astaxanthin may modulate the inflammatory response in a mouse model of atopic dermatitis and has an anti-inflammatory effect.