The results suggest that QSLN-2, prepared with a surfactant content of 2%, could be used as useful skin delivery system for transdermal delivery of hydrophobic antioxidants such as quercetin.

No abstract

Inhibitory effect against melanogenesis and the tyrosinase inhibitory activity of ethyl acetate (EtOAc) and methylene chloride fractions of 80% methanol extracts of mung bean ( L.) seeds and sprouts were determined. EtOAc extract fractions from mung bean sprouts germinated for 12 h (33.5%), 1 day (56.5%), and 2 days (47.9%) inhibited melanogenesis more effectively than arbutin (16.3%). The tyrosinase inhibitory activity was higher in an EtOAc extract fraction from mung bean sprouts germinated for 2 days (70.5%). EtOAc extract fractions from mung bean sprouts germinated for 1 day showed excellent whitening effects due to the flavone vitexin. Extracts from mung bean sprouts germinated for 1 day can be used as a novel whitening cosmeceutical ingredient.

In this work, licorice extracts were prepared using various extraction conditions such as extraction solvent, temperature, and time from Glycyrrhiza uralensis (G. uralensis) produced in Korea and China and Glycyrrhiza glabra (G. glabra) in Uzbekistan. The optimum extraction condition was selected from the extraction yields and antioxidative activities of extracts. Korea licorice extracts showed the highest free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity (46.05%) under the extraction condition of 85% ethanol at 60 ℃ for 6 hours. The prominent ROS (reactive oxygen species) scavenging activity using luminol-dependent chemiluminescence assay and the cellular protective effect against 1 O2 induced cellular membrane damage were also shown from the extracts obtained from the same