A 3-year-old boy developed idiopathic thrombocytopenic purpura (ITP) and Perthes' disease concurrently. Antiphospholipid antibodies were detected in the serum of the patient. Therefore, it is possible that Perthes' disease in this patient might be one of the manifestations of ITP-associated antiphospholipid syndrome.

T cell activation and T cell receptor variable (V) regions were studied with monoclonal antibodies in peripheral blood lymphocytes from 22 patients with measles. Increased (> 5%) activated T cells (HLA‐DR+ CD3+ cells) were noted in 14 of the 22 patients. Elevations of Vβ5+ and Vβ8 + T cells were observed in two and four patients, respectively, and appeared to be associated with T cell activation. The duration of fever was significantly prolonged in those with increased (> 10%) activated T cells (p < 0.01). These results suggest that T cell activation and the preferential expansion of Vβ8+ and Vβ5+ T cells are associated with the pathogenic process of measles.