Four pamamyciu..(j07-degraded products-desdimethylaminopamamycin-607, a macrodiolide ring-opened compound, and two constitutent hydroxy acids-were prepared, and their aerial mycelium-inducing activity was measured. The hydroxy acid L part with a dimethyl amino group was the principal component responsible for activity. The macrodiolide ring itself was dispensable, but only hydroxy acid L showed very weak activity.
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