Low-level laser acupuncture (LLLA) produces photobiomodulation through acupuncture point and is an alternative to low-level laser therapy. Although the analgesic effect of LLLA on chronic pain has been proven, its effect on acute postincisional pain has yet to be investigated. A plantar incision (PI) model was used to mimic human postsurgical pain. Male adult rats received GaAlAs laser irradiation at the right ST36 acupoint immediately after operation and on the following 4 days. Three laser treatment groups (two red laser groups with a 30- or 15-min treatment duration and one 30-min near-infrared laser group) were compared with sham LLLA and naive groups and an electroacupuncture (EA) group (separate study). Behavioral withdrawal thresholds of both hind paws were measured before and after incision. Expression of mitogen-activated protein kinases (p-ERK and p-p38), inducible nitric oxide synthase (iNOS), and tumor necrosis factor (TNF) in the spinal cord was analyzed. All three LLLA treatments attenuated post-PI tactile allodynia in the ipsilateral paw, but only the 30-min red laser treatment affected the contralateral paw and had similar efficacy to that of EA. All laser treatments barely reduced heat hyperalgesia in both hind paws. At 3 days after PI, the 30-min red laser group showed reversed increases of PI-induced p-ERK, p-p38, and iNOS but not TNF expression in the spinal cord. Repetitive LLLA treatments ameliorated PI-induced mechanical pain. The inhibition of multiple sensitization signals highlights the unique clinical role of LLLA. Thus, LLLA is an alternative to EA as an adjuvant for postoperative pain control.Electronic supplementary materialThe online version of this article (10.1007/s10103-017-2367-7) contains supplementary material, which is available to authorized users.
For assessing the joint operations command and staff objectively, the paper established a joint command personnel ability evaluation of multilayer index system. In view of the majority of interval-valued intuitionistic fuzzy information that is only used for single layer multi attribute index system. In the case of the two grade index attribute weights unknown, we utilized the score vector projection formula and obtained the pros and cons of the commanders in all levels under the one class index attribute. Finally we apply the ladder structure comprehensive assessment method to get the comprehensive ranking. It provide a certain basis for the selection of the joint operational commanders
The concentration signal of silica powder in the fluidizing gas i.e. air under different operation conditions were determined. The pretreating effects of concentration signal of silica powder by low pass filtering, wavelet transform de-noising and wavelet packet de-noising were compared. And the optimum method of de-noising has been determined.
The particle concentration signals of silicon powder in the fluidizing gas i.e. air under different operating conditions were determined. The diameter of silicon particles, operating velocity, radial distance and axial distance are used as input vector; the mean value of particle concentration signal in the silicon power fluidized bed is used as a target vector. The RBF neural network is applied to build the predicted model of the mean value in silicon power fluidized bed. The result shows that the prediction of mean value through the RBF neural network is prior to that by BP neural network, and its error is less than 0.2%.
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