An epidemiological study on brugian filariasis was carried out in endemic areas including Cheju Island in Korea, with a brief review of literatures.The results showed that the incidence among residents has remarkably decreased in Cheju Island, which was the main endemic area. Reviewing available informations on the prevalence of filariasis reported in recent years and also judging from the present socio-economic conditions which enable people to practice personal protection against mosquitos, it can be said with confidence that filariasis has almost disappeared from Cheju Island and inland areas. The disease is considered to remain at a low level of endemicity in Hugsan Islands. Certainly mass diethylcarbamazine (DEC) treatment carried out in Cheju Island in the 1960s and 1970s and remarkable economic growth followed by improved living standard and altered life-style of inhabitants could all have combined effects on the disappearance of this mosquito-borne diseae in this island. If the present trends go on, the possibility of resurgence of filariasis in Cheju Island is hardly postulated.

Departmeη t 0/ Diagnostic Radiology, Kyiμηg Hee [}，η iversity， College 0/ Medicine R adiological investigation in patients with clonorchiasis is very important as this is the only m ethod of evalu ating the severity of clonorchiasis. In order to correlate the radiologic and pathologic findings of clonorchiasis , fourteen rabbits infested with C lonorchis sinensis and fi ve control rabbits were examined radiologically by ultrasonography, computed tomography and chola n giogr aphy and the results were correlated with pathologic findings . Dilatation of th e in trahepatic small bile ducts of the liver was due to obstructio n by f1 ukes: oval or elliptical small filling defects or irregular margin of the bile ducts on cholangiogr am or intraluminal echoes on sonogram represented f1 ukes per se;periductal thickening on sonogram and periductal enhancement of bile ducts on CT were due to inf1 ammatory cell infiltration , adenomatous hyperplasia and periductal fibrosis; band like enhancement at the periphery of the liver on CT represented proliferated bile ducts , destruction of liver cells and r esultant fibrosisThe study confirmed the pathological bases for the radiological findings of clonorchiasis in liver and bile ducts and will , perhaps, serve as a basis for the future radiologic-pathological correlation of clonorchiasis and in further clinical and experimental researches in the biliary tract di seases

1. The evaluation of the effects of anthelmintic drug dose was done by the eggs reduction and the eggs negative conversion rate. 2. The drug dose according to the age of the patient was estimated by the formula of Augsberger, the dose according to the body weight of patient was estimated by the Rule of Six, and the dose to the body surface of the patient was estimated by the formula of Costeff. 3. It is considered that the application of the drug dose according to the age of the patient resulted in reduction of dose in the younger patient, and resulted in the excess dose in older patient. The application of the drug dose according to the body weight also resulted in the reduction of dose in the lighter patient and the excess dose in the heavier patient. 4. It is suggested that the application of drug dose according to the body surface is more reasonable than those by the age and the body weight. The value of this application was also proved to be medium value between those of age method and body weight method.