Research on the National Spherical Torus Experiment, NSTX, targets physics understanding needed for extrapolation to a steady-state ST Fusion Nuclear Science Facility, pilot plant, or DEMO. The unique ST operational space is leveraged to test physics theories for next-step tokamak operation, including ITER. Present research also examines implications for the coming device upgrade, NSTX-U. An energy confinement time, τ E , scaling unified for varied wall conditions exhibits a strong improvement of B T τ E with decreased electron collisionality, accentuated by lithium (Li) wall conditioning. This result is consistent with nonlinear microtearing simulations that match the experimental electron diffusivity quantitatively and predict reduced electron heat transport at lower collisionality. Beam-emission spectroscopy measurements in the steep gradient region of the pedestal indicate the poloidal correlation length of turbulence of about ten ion gyroradii increases at higher electron density gradient and lower T i gradient, consistent with turbulence caused by trapped electron instabilities. Density fluctuations in the pedestal top region indicate ion-scale microturbulence compatible with ion temperature gradient and/or kinetic ballooning mode instabilities. Plasma characteristics change nearly continuously with increasing Li evaporation and edge localized modes (ELMs) stabilize due to edge density gradient alteration. Global mode stability studies show stabilizing resonant kinetic effects are enhanced at lower collisionality, but in stark contrast have almost no dependence on collisionality when the plasma is off-resonance. Combined resistive wall mode radial and poloidal field sensor feedback was used to control n = 1 perturbations and improve stability. The disruption probability due to unstable resistive wall modes (RWMs) was surprisingly reduced at very high β N /l i > 10 consistent with low frequency magnetohydrodynamic spectroscopy measurements of mode stability. Greater instability seen at intermediate β N is consistent with decreased kinetic RWM stabilization. A model-based RWM state-space controller produced long-pulse discharges exceeding β N = 6.4 and β N /l i = 13. Precursor analysis shows 96.3% of disruptions can be predicted with 10 ms warning and a false positive rate of only 2.8%. Disruption halo currents rotate toroidally and can have significant toroidal asymmetry. of this phenomenon in designing future RF systems. The snowflake divertor configuration enhanced by radiative detachment showed large reductions in both steady-state and ELM heat fluxes (ELMing peak values down from 19 MW m −2 to less than 1.5 MW m −2 ). Toroidal asymmetry of heat deposition was observed during ELMs or by 3D fields. The heating power required for accessing H-mode decreased by 30% as the triangularity was decreased by moving the X-point to larger radius, consistent with calculations of the dependence of E × B shear in the edge region on ion heat flux and X-point radius. Co-axial helicity injection reduced the induct...

Since the installation of an ITER-like wall, the JET programme has focused on the consolidation of ITER design choices and the preparation for ITER operation, with a specific emphasis given to the bulk tungsten melt experiment, which has been crucial for the final decision on the material choice for the day-one tungsten divertor in ITER. Integrated scenarios have been progressed with the re-establishment of long-pulse, high-confinement H-modes by optimizing the magnetic configuration and the use of ICRH to avoid tungsten impurity accumulation. Stationary discharges with detached divertor conditions and small edge localized modes have been demonstrated by nitrogen seeding. The differences in confinement and pedestal behaviour before and after the ITER-like wall installation have been better characterized towards the development of high fusion yield scenarios in DT. Post-mortem analyses of the plasma-facing components have confirmed the previously reported low fuel retention obtained by gas balance and shown that the pattern of deposition within the divertor has changed significantly with respect to the JET carbon wall campaigns due to the absence of thermally activated chemical erosion of beryllium in contrast to carbon. Transport to remote areas is almost absent and two orders of magnitude less material is found in the divertor.

High-spin states in 161 Er have been studied experimentally using the 150 Nd( 16 O,5n) reaction at a beam energy of 86 MeV. The 5/2 + [642], 3/2 − [521], and 11/2 − [505] bands are extended up to high-spin states, and particularly the α = −1/2 branch of the ground state 3/2 − [521] band is revised significantly. The relatively enhanced E1 transitions from the 3/2 − [521] band to the 5/2 + [642] band are observed. The band properties are analyzed within the framework of a triaxial particle-rotor model, and near-prolate shape and triaxial deformation are proposed to the 3/2 − [521] and 5/2 + [642] bands, respectively. Signature inversion occurs in the 3/2 − [521] band after the band crossing in 161 Er, and the systematics of the signature inversion associated with the 3/2 − [521] configuration are discussed. By analyzing the properties of the relatively enhanced E1 transitions, it is found that the R(E1/E2) values show angular momentum dependence before the band crossing, and these enhanced E1 transitions could be attributed to octupole softness.

Highlights UCA1 is upregulated in both osteosarcoma tissues and cell lines. UCA1 promotes osteosarcoma metastasis both in vitro and in vivo. UCA1 increased CREB1 expression by functioning as a ceRNA of CREB1 against miR-582. The pro-metastasis role of UCA1 is achieved by promoting EMT. UCA1 enhances EMT through CREB1-mediated the PI3K/Akt/mTOR pathway.