The Industry 4.0 era requires new quality management systems due to the ever increasing complexity of the global business environment and the advent of advanced digital technologies. This study presents new ideas for predictive quality management based on an extensive review of the literature on quality management and five realworld cases of predictive quality management based on new technologies. The results of the study indicate that advanced technology enabled predictive maintenance can be applied in various industries by leveraging big data analytics, smart sensors, artificial intelligence (AI), and platform construction. Such predictive quality management systems can become living ecosystems that can perform cause-effect analysis, big data monitoring and analytics, and effective decision-making in real time. This study proposes several practical implications for actual design and implementation of effective predictive quality management systems in the Industry 4.0 era. However, the living predictive quality management ecosystem should be the product of the organizational culture that nurtures collaborative efforts of all stakeholders, sharing of information, and co-creation of shared goals.
Microsomal oleic acid desaturase (FAD2) catalyzes the first committed step of the biosynthesis of polyunsaturated fatty acids via extra-plastidial desaturation of oleic acid to linoleic acid. In the regulatory mechanism controlling seed-specific SeFAD2 expression, trans-activation of the seed-specific SeFAD2 promoter is mediated by the SebHLH transcription factor (Kim et al. in Plant Mol Biol 64:453-466, 2007). In this study, a protein interacting with SebHLH was isolated from yeast two-hybrid analysis. The protein shares approximately 80% sequence identity with other putative casein kinases and was named SeCKI (Sesame Casein Kinase I). SeCKI transcripts were predominantly expressed in developing sesame seeds and were induced approximately threefold by exogenous application of ABA. eGFP:SeCKI fusion protein was localized to the nucleus. The SeCKI protein specifically bound to SebHLH. The SeCKI protein was autophosphorylated in a calcium-independent manner and transphosphorylated the SebHLH protein. Both the SebHLH and the SeCKI genes or both the SebHLH and mutated SemCKI (K182G) genes, under the control of CaMV 35S promoter, and the GUS reporter gene driven by SeFAD2 promoter containing E- and G-Box motifs were co-expressed in developing sesame seeds. This co-expression revealed that SeCKI enhanced the SebHLH-mediated transactivation of the SeFAD2 gene promoter via phosphorylation of the SebHLH transcription factor.
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