Tuberculosis remains one of the most dangerous and socially significant diseases in the world. Diagnostic imaging of pulmonary tuberculosis is being improved every year, new algorithms, technologies and methods are being introduced, what create a positive effect on the detection of tuberculosis. However, the diagnosis of tuberculosis remains a challenge. Digital fluorography remains the primary screening method, and computed tomography (CT) is used for more detailed analysis. This should be noted that there is a positive trend towards the application of low-dose computed tomography (LDCT), which is invaluable for screening studies. The leading place among radiopaque studies is CT with bolus enhancement, which helps to differentiate tuberculosis with other lung diseases. Such diagnostic methods as single-photon emission computed tomography, magnetic resonance imaging (MRI), and diffusion-weighted MRI are used individually as an additional source of information.