Growth kinetics of human breast tumor cell in the presence of doxorubicin was studied using the method of UV spectrophotometery. Parameters of ecotoxicological cell growth model were established. Cell number predicted by the model equation corresponded to the observed cell count within the experimental error. The therapeutic dose of doxorubicin hydrochloride was determined.
Combined toxicity of inorganic substances: Ag(I)--Cu(II), Cr(VI)--Ni(II) is studied in a culture of Saccharomyees cerevisiae yeasts. The dynamics of yeast growth in the presence of individual metals an their combinations is examined. A diagram method for the evaluation of combined toxicity is proposed.
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