No abstract

Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery, we observed recovery of all layers of the jejunum wall at the site of injury and complete degradation of the implant material.

This article presents the experience of treating a child with stenosis of a colo-rectal instrumental anastomosis imposed due to Hirschsprung’s disease.

Chronic appendicitis is a pathologic condition caused by a slowly developing, flaccid and long-lasting inflammatory process in the appendix of the cecum. A 7-year-old child with chronic appendicitis and appendix penetration into the posterior wall of the bladder was treated at the surgical department of Vladimirovsky Moscow Region Clinical Institute. Such a combined pathology caused some difficulties in diagnostics. Chronic appendicitis is considered as an independent nosological form and can be masked by various surgical conditions.

A new classification of limb‑girdle muscular dystrophy, which was adopted in 2018, is given. The reasons why there was a need to revise the classification are indicated. A new definition of this pathology is given. The diseases that were excluded from the new classification of limb‑girdle muscular dystrophy due to inconsistency with the new definition of this form of pathology are given. A comparison of the new and old classification of this group of muscular dystrophies is given. The genes responsible for the development of various forms of this pathology are indicated, as well as proteins of striated musculature, the synthesis of which is disrupted. It has been shown that a mutation in one gene can lead to different types of inheritance of limb‑girdle muscular dystrophy, which is important to take into account when conducting prenatal diagnostics. The new classification will allow introducing new forms of this pathology as new mutations in disease genes are detected.