Cycloaddition of levoglucosenone to 7-methoxy-4-vinyl-1,2-dihydronaphthalene has been studied under different conditions, including heating under atmospheric pressure, in a sealed ampule, and under high pressure, as well as under microwave irradiation and in the presence of various catalysts. The chiral Diels-Alder adduct thus obtained can be used in the synthesis of estrone and its analogs.
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