Background: Pertolongan persalinan merupakan faktor penting dalam upaya menurunkan angka kematian ibu dan anak. Di Indonesia pemanfaatan pertolongan persalinan oleh tenaga kesehatan yang kompeten masih kurang dibandingkan target yang diharapkan, termasuk di Kecamatan Klabang Kabupaten Bondowoso pada tahun 2018 hanya mencapai 86,10%.Objectives: Penelitian ini bertujuan untuk menganalisis pengaruh penyuluhan berbasis video whatsapp tentang persalinan terhadap pengetahuan dan sikap ibu hamil trimester III di Puskesmas Klabang Kabupaten Bondowoso.Design: Penelitian ini menggunakan desain One Group Pretest-Posttest. Populasi penelitian ini adalah semua ibu hamil Trimester III di wilayah kerja Puskesmas Klabang yang diperkirakan melahirkan pada bulan Mei-Juni tahun 2019, dengan jumlah sampel sebesar 33 orang. Analisis data menggunakan uji Wilcoxon dengan nilai signifikansi sebelum dan setelah penyuluhan sebesar 0,000 < 0,005.Results: dari 33 responden, 20 responden menunjukkan adanya peningkatan sikap yang positif setelah diberikan eksperimen. Hasil analisa statistik dengan uji Wilcoxon diperoleh nilai p- value 0,000 (p<0,05), artinya terdapat pengaruhartinya terdapat perbedaan sikap sebelum dan sesudah dilakukan penyuluhan berbasis video whatsapp tentang persalinan. Sehingga H0 ditolak yang berarti bahwa ada perbedaan atau hipotesa peneliti diterima.Conclusions: Disimpulkan bahwa ada pengaruh penyuluhan berbasis video whatsapp tentang persalinan terhadap pengetahuan dan sikap ibu hamil trimester III di Puskesmas Klabang Kabupaten Bondowoso.
ABSTRAK Pertolongan persalinan merupakan faktor penting dalam upaya menurunkan angka kematian ibu dan bayi. Di Indonesia pemanfaatan pertolongan persalinan oleh tenaga kesehatan yang kompeten masih kurang dibandingkan dengan target yang diharapkan, salah satunya di Kecamatan Klabang Kabupaten Bondowoso pada tahun 2018 hanya mencapai 86,10%. Penelitian ini bertujuan untuk menganalisis pengaruh penyuluhan berbasis video whatsapp tentang persalinan terhadap pengetahuan dan sikap ibu hamil trimester III di Puskesmas Klabang Kabupaten Bondowoso. Penelitian ini menggunakan desain One Group Pretest-Posttest. Populasi pada penelitian ini yaitu semua ibu hamil Trimester III di wilayah kerja Puskesmas Klabang yang diperkirakan melahirkan pada bulan Mei-Juni tahun 2019, dengan jumlah sampel sebesar 33 orang. Analisis data menggunakan uji Wilcoxon dengan nilai signifikansi sebelum dan setelah penyuluhan sebesar 0,000 < 0,005. Terdapat pengaruh penyuluhan berbasis video whatsapp tentang persalinan terhadap pengetahuan dan sikap ibu hamil trimester III di Puskesmas Klabang Kabupaten Bondowoso. Kata Kunci : Persalinan, Penyuluhan Kesehatan, Video WHATSAPP ABSTRACT Childbirth assistance is an important factor in efforts to reduce maternal and infant mortality. In Indonesia the use of childbirth assistance by competent health workers is still below the expected target, including in Klabang Subdistrict, Bondowoso Regency in 2018 only reach 86.10%. This study aims to analyze the effect of whatsapp video-based counseling about childbirth on the knowledge and attitudes of thirdmester pregnant women in the Puskesmas Klabang, Bondowoso Regency. This study used a One Group Pretest-Posttest design. The population of this study were all thirdmester pregnant women in the working area of the Klabang Community Health Center who were expected to give birth in May-June 2019, with a total sample of 33 people. Data analysis used the Wilcoxon test with a significance value before and after counseling of 0,000 <0.005. There was an influence of whatsapp video-based counseling about childbirth on the knowledge and attitudes of trimester III pregnant women in the Puskesmas Klabang, Bondowoso Regency.
Antioxidant pentapeptides are pentapeptide compounds that have antioxidant activity. One of the pentapeptide compounds that have antioxidant activity is FWKVV. FWKVV is a linear pentapeptide with the amino acid sequence phenylalanine-tryptophan-lysine-valine-valine, which was first isolated to hydrolyzate the muscle protein of Miiuy croaker (Miichthysmiiuy). In addition to isolation, FWKVV compounds can be produced by the peptide synthesis method because this method requires a shorter time than the isolation method from natural materials. Synthesis methods commonly used are solution-phase peptide synthesis and solid-phase peptide synthesis (SPPS). However, the SPSS method is more efficient because it does not require purification in every process. The purpose of this study was to synthesize FWKVV compounds using the SPPS method and test their antioxidant activity. FWKVV has been synthesized using the SPPS method with HBTU/HOBt coupling reagent and Fmoc protective group. The FWKVV crud produced was 148.8 mg and had antioxidant activity against DPPH radicals with an IC50 value of 4.2 mg/mL.
Dengue Hemorrhagic Fever (DHF) is also one of the infectious diseases that often cause extraordinary events. Low awareness to maintain environmental cleanliness and lack of public knowledge about eradicating mosquito nests to prevent Dengue Hemorrhagic Fever. This study aims to identify the relationship between the level of knowledge and the family attitudes of dengue hemorrhagic fever sufferers regarding the eradication of mosquito nests (PSN) in the work area of the Curahdami Health Center in Bondowoso Regency.Types of quantitative research designs. population and sample of 37 respondents by using total sampling. Data collection techniques used the Likert scale questionnaire to measure Knowledge Level and bivariate analysis was performed to determine the relationship between variables using Spearman's Rho. Statistical test results of Spearman's Rho. Obtained p-value 0.002 which means that Ho is rejected and H1 is accepted. There is a relationship between the level of knowledge with the family attitudes of dengue hemorrhagic fever sufferers about the eradication of mosquito nets in the work area of the bulk health center with a correlation coefficient of 0.487.From the results of this study, the level of knowledge of families suffering from dengue fever in eradicating mosquito nests in the Bondowoso district health center area is good.
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