We describe a powerful approach, component plane presentation integrated self-organizing map (SOM), for the analysis of microarray data. This approach allows the display of multi-dimensional SOM outputs of microarray data in multiple sample speci¢c presentations, providing distinct advantages in visual inspection of biological signi¢cances of genes clustered in each map unit with respect to each RNA sample. Bene¢cial potentials of the approach are highlighted by processing microarray data from yeast cells as well as human breast malignancies. ß

The study reviewed coping and help-seeking behaviour among Hong Kong Chinese family care-givers of older people diagnosed with dementia. A convenience sample of those caring for family members with dementia (N=11) was recruited in Hong Kong. Semi-structured interviews were conducted, transcribed and analysed using NVivo. The study found evidence of distinct Chinese coping strategies that focused upon internal self-regulation, forbearance and family obligations. In terms of help-seeking behaviour, these care-givers expressed great concern about bothering their family members. When there is a desperate need for help, they turn to community services. Results are discussed in the context of both traditional Chinese cultural values as well as the modern transformations of the Chinese society. In particular, Eastern philosophical teachings tend to focus on changing personal inner perception and thoughts rather than attempting to change the environment. Although family obligations have been traditionally upheld, many modern Chinese societies are undergoing social and demographic changes, resulting in marked decline in multi-generational households. Our findings can have applications not only for Chinese cities but also may have implications to the West as strong well-established Chinese communities are widespread.

It is demonstrated that the HAPA model could be applied to understand safer sex behavior among Chinese MSM. Its principles can help develop HIV prevention programs targeting safer sex practices by MSM.

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