Adenoid cystic carcinoma arising from the peripheral lung is rare. Here, we describe adenoid cystic carcinoma that developed in the peripherally in S 9 of the right lower lobe of an 84-year-old woman. Cell blocks prepared from the bronchial wash specimens exhibited the cribriform formation. An immunohistochemical examination of the surgically resected tumor revealed positive thyroid transcription factor-1 and c-kit staining. Exons 9 and 11 of c-kit in tumor cells were not mutated. We compared the clinical features of this patient with those of 10 others described in the English-language literature.

A 45-year-old man was referred to our hospital for examination of a gastric subepithelial lesion (SEL). Esophagogastroduodenoscopy revealed an SEL approximately 15 mm in diameter and covered with normal mucosa in the posterior wall of the proximal gastric body (Figure 1). Endoscopic ultrasound (EUS) showed heterogeneous echogenicity and cystic structures in the lesion, which seemed to partially interrupt the fourth layer of the gastric wall (Figure 2). We suspected a malignant tumor and performed EUS-guided fine-needle aspiration (EUS-FNA). Three passes were performed using 22-gauge needles (EZ Shot 3; Olympus, Tokyo, Japan) without a rapid on-site evaluation. However, the recovered specimens were inadequate to confirm the diagnosis. The tumor did not protrude outside the gastric wall; subsequently, we considered endoscopic mucosal cutting biopsy.

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