[reaction: see text] Primary amines reacted with carbonate salts (Na2CO3, K2CO3, Cs2CO3, and Ag2CO3) and halomethyloxiranes in the presence of a base such as DBU or TEA to give oxazolidinones in high yields. The use of K2CO3 among these carbonate gave the best yield in this synthesis. A reaction mechanism was proposed that the oxazolidinone was obtained from an oxazinanone intermediate via a bicyclo[2.2.1] intermediate. The present reaction can be widely applied to convenient synthesis of useful N-substituted oxazolidinones and chiral oxazolidinones.

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Synopsis Profiles of 2.8 MeV H+ microbeam extracted from a single tapered glass capillary optics were meas-ured by two methods for a future irradiation to an outer organ of insect target. The halo component was analyzed to be 575 μm in full width at half maximum (FWHM) at a plastic tracking detector CR-39 located 1 mm down-stream of the capillary. The core component was examined by knife-edge method according to the ion energies. The profiles consisting of more energy-loss events have wider FWHM, which can be reduced by Al thin layers.