Winding vine-shaped bithiophene was synthesized through the nosyl (2-nitorobenzene sulfonyl) cyclization protocol. The reaction of bithiophene bearing bromomethyl groups at the 3,3'-positions with nosylated 1,2-ethylenediamine in the presence of potassium carbonate afforded the annulated product in excellent yield. The obtained bithiophene was found to contain a 10-membered ring, which was confirmed by X-ray analysis. The related nosyldiamine bearing a tri-or tetramethylene group also reacted in a similar manner, affording 11-or 12-membered macrocycle, respectively.

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