Background: c-Abl and DGK␣ are important enzymes for many cellular processes. However, substrates of c-Abl and the regulation mechanism of DGK␣ are not fully understood. Results: c-Abl directly phosphorylates DGK␣ at Tyr-218.
Conclusion:The c-Abl phosphorylation regulates the serum-induced nuclear export of DGK␣. Significance: The c-Abl phosphorylation contributes to the spatio-temporal regulation of DGK␣.
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