Echinococcosis represents a major public health and economic issue in many countries and is considered a neglected tropical disease by the World Health Organization. 1 This zoonotic disease is caused by cestodes of the Echinococcus species. While some Echinococcus species are transmitted in life cycles that involve predominantly domestic animals (eg dog-livestock cycles), others are wildlife parasites that do or do not interact with domestic transmission. In many cases, life cycle patterns of the same parasite species differ according to

Background: The migration of humans and climatic and environmental changes cause the emergence of infectious diseases. This study aimed to investigate the changes in the molecular epidemiology of the echinococcosis in the southeast region of Turkey after migrations. Methods: Overall, 159 tissues samples were taken from suspected cases of echinococcosis at the Kilis State Hospital in the southeast region of Turkey. All of the tissues samples were analyzed using histopathology methods, PCR, Real-time PCR methods, DNA sequencing, and phylogenetic analyses in laboratories. Results: The positivity values of the histopathology, the polymerase chain reaction, and the Real-time PCR methods were found to be 14.5% (23/159), 15.7% (25/159), and 16.9% (27/159), respectively. 32.0 % (8/25) E. multilocularis of Echinococcus isolates and 68% (17/25) E. granulosus of Echinococcus isolates were identified using PCR methods. 58.8% (10/17) of the E. granulosus isolates were found to be Genotype 1% and 41.2% (7/17) E. granulosus isolates were found to be Genotype 3. Conclusion: Molecular methods play an important role in the epidemiology, treatment, and diagnosis of diseases. Increasing immigration in a geographical area may create social, economic, and health problems in that area. For this reason, epidemiological studies of infectious diseases should be updated in areas with immigration.

Amaç: Bu çalışmadaki amacımız biyopsi sonucu rektum kanseri tanısı alan preoperatif Magnetik rezonans (MR) ile evrelemesinde lokal ileri evre rektum tümörü olduğu saptanan ve preoperatif kemo-radyoterapi (KRT) almış olan hastalarda KRT öncesi ve sonrası yapılan MR incelemesi ile patoloji bulgularını retrospektif olarak karşılaştırmaktır. Gereç ve

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