-It is shown that use of coal-water slurry fuel (CWF) is most preferable for reduction of sulfur oxide content during combustion of coal fuel by feeding of sulfur capture agents (SCA) in the burning area. The technique of thermodynamic analysis of chemical reactions in the process of CWF burning was developed. In this case, the optimal temperature conditions have been determined as required for the effective reduction of sulfur oxides in flue gases when using different types of SCA. According to the results of calculating the composition of CWF combustion products when entering various substances in the burner space as SCA it has been determined that magnesite, calcite, and dolomite are the most effective natural minerals. The reliability of the results obtained is confirmed by experimental studies of burning CWFs prepared from Bulgarian high-sulfur coal Keywords-sulfur capture agent; water-coal slurry fuel; thermodynamic analysis; vortex combustion of coal fuel