Objective: The objective of this research was the development of cream with sapropel extract on the emulsifying base and the investigation of the possibility for cream samples to be in future applied in medicine, cosmetics, and veterinary.Methods: To carry out the research a set of methods (centrifugal, thermal, and potentiometric) to analyze colloidal and thermal stability and determine pH values of the tested samples were used. Organoleptic characteristics of the tested samples and possible signs of physical instability were studied. Rheological properties of the samples were determined on the rotating viscometer. The method of microscopic analysis was carried out to analyze the stability of the emulsion system.Results: The research outcomes revealed that all the prototype samples have thermal and colloid stability, neutral pH value, and consistency that depends on the content of the oil phase and the emulsifying mixture. The samples, containing 15% of Vaseline oil and 4% and 6% of emulsifier no. 1, have low viscosity indexes, and the sample with 10% of emulsifier has a rather dense consistency. The samples containing 20% of oil phase possess unsatisfactory organoleptic properties. Since the sample with 4% of emulsifier possessed low rates of viscosity and phase separation occurred during its storage.Microscopic studies have shown that the sample containing 6% of emulsifier no. 1 exhibits monodisperse and a uniform roundness of drops that indicates the stability of the system.Conclusion: The outcome of the research is the development of the composition of the cream with sapropel extract with the emulsifying base containing 15% of corn oil, 6% of emulsifier no. 1, and 1% of Cetostearyl alcohol and purified water.
the article presents the results of studying the technological properties of medicinal plant raw materials Siberian Statice (Limonium gmelinii), namely specific, volumetric, bulk density, determination of absorption coefficient and swelling rate, as well as porosity, free volume layer and fractional composition. Grinded raw materials from the aboveground part of Siberian Statice, which included stems, inflorescences, flowers was the object of the study. Siberian Staticea (Limonium gmelinii) is a perennial herbaceous bare plant of the Kermek genus, which contains tannins, flavonoids, hydroxycinnamic acids, anthocyanins, coumarins, carbohydrates, polysaccharides, organic acids, amino acids and others. The raw material in the Genichesk district of the Kherson region was harvested in 2021. The study of basic technological properties was carried out according to generally accepted methods, which are listed in the State Pharmacopoeia of Ukraine. The data obtained during the study indicate that the composition of the grinded raw material is polydisperse and it is not possible to determine one predominant fraction. Particles with a size of 2,8-1,0 mm are about 80% of the composition. This diversity of composition can be explained by the fact that the studied aboveground part of plant raw materials includes a thick-branched stem, inflorescences with small regular flowers. The humidity of the studied raw materials is 0,23%. The specific density of raw materials is 1,3446 ± 0,0073 g/cm3, and the volumetric density of plant raw materials is 0,4679 ± 0,0450 g/cm3. Bulk mass after shrinkage decreased from 80 to 69, which is 13,75%. Volumetric shrinkage increased from 0,1251 g/cm3 to 0,1436 g/cm3. Indicators of porosity, porosity and free volume layer (0,6933 g/cm3, 0,7326 g/cm3, 0,9073 g/cm3, respectively) are quite high, which indicates a good absorption capacity of raw materials. The average value of the absorption coefficient was 6,33 ± 0,34, which indicates a high cost of extractant, and the swelling rate shows that the investigated raw material doesn’t swell, this indicates the presence of pores inside the stem, where the extractant is retained, but does not increase linear dimensions and volume plant raw materials. The technological properties of Siberian Statice (Limonium gmelinii) raw materials have been experimentally determined, which allow choosing the optimal extraction methods for the studied raw materials, namely the extraction method, the ratio of raw materials: extractant, the nature of the extractant.
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