To improve ethanol enrichment performance using ultrasonic atomization, ultrafine bubbles (UFB) were added to an ethanol aqueous solution. The ethanol concentration in the solution and the flow rate of carrier gas were changed, and the effect of UFB on the ethanol concentration in the collected mist was investigated. For all conditions, the ethanol concentration in the collected mist with UFB was higher than that without UFB. Especially, the enrichment effect by UFB was remarkable when the ethanol concentration in the solution and the flow rate of carrier gas were low.