Primary ureteral fibroepithelial polyps (UFPs) are rare benign tumors of mesodermal origin. The majority UFPs are observed in the proximal part of the ureter and most commonly on the left side. The mean diameter of UFP is reported to be <5 cm. We herein present a rare case of a long primary ureteral polyp originating from the lower ureter in a 53-year-old woman. Following computed tomography, magnetic resonance imaging, retrograde pyelography and ureteroscopic examination, a preliminary diagnosis of giant primary lower ureteral polyp protruding into the bladder was obtained. Polyp resection and resection of the narrow ureteral segment with a V-shaped end-to-end anastomosis were performed. The length of this polyp was 15.0 cm, and the final pathological diagnosis was UFP. No recurrence or ureteral stenosis were observed at the 12-month follow-up. A supplementary review of previously published cases and related literature is also included.

Purpose:The aim of this study is to preliminarily investigate the expression of mitochondrial fusion protein 1 (MFN1) in a lens-induced animal myopia (LIM) model and to explore the relationship between MFN1 and the visual development.Materials and Methods:MFN1 gene expression in guinea pigs was examined during the development of minus LIM, 15 tri-colored guinea pigs were obtained, and one eye of each pig was randomly selected and treated with −7.00D lenses. Ocular refraction and axial length were collected before intervention and 1, 2, and 3 weeks after intervention. After the refraction and axial length measurements at 1, 2, and 3 weeks of lens intervention, five guinea pigs were randomly selected. MFN1 expression in the retina of both eyes was tested by immunohistochemistry technique.Results:MFN1-positive cells could be observed in the retina of both eyes. The positive cells in the LIM eyes were staining deeper, and much more positive cells could be observed. Furthermore, MFN1-positive expression could be seen mainly in ganglion cells after 1 week of minus lens intervention, and with time extension, more and more positive cells appeared in the rod-cone cell and bipolar cell layer, and this phenomenon could not be found in the normal control eyes.Conclusion:This study suggested that MFN1 might be correlated to the development of myopia.