Purpose: This study aimed to investigate the effects of health-promoting behaviors (HPB), marital intimacy, and parenting stress on the quality of life (QoL) of low-income women with young children in Korea, an underserved group.Methods: This cross-sectional survey employed a descriptive correlational design. Using convenience sampling, 123 low-income women with children younger than 6 years were recruited from 14 health and community centers in a Jeonju Korea from June 2020 to May 2021. Participants completed a questionnaire on QoL, HPB, marital intimacy, and parenting stress. Data were analyzed using descriptive statistics, independent t-test, analysis of variance, Pearson correlation, and hierarchical regression analysis.Results: Participants, who were on average 37.41±3.65 years old and had 1 to 2 children (n=98, 79.7%), reported a mid-level (3.14 out of 1–5) of QoL. Marital intimacy (β=.38, p<.001) was the most influential factor on the QoL of low-income women with young children. In descending order, HPB (β=.35, p<.001) and non-employment status (β=–.21, p=.003) had a significant influence on QoL (F=15.64, p <.001), and the overall explanatory power was 49.0%. Conclusion: Considering the mid-level QoL of low-income women with young children, programs aimed at improving the QoL of low-income women need to promote marital intimacy and maintain HPB, while considering their employment status. Strategies that include couple counseling, health care to encourage healthy lifestyles, and reemployment education are needed.