Before the coronavirus disease 2019 (COVID-19) pandemic, laboratory medicine management activities mainly remain inside of the laboratory, including reagent and instrument maintenance, daily quality assessment, errors elimination, turnaround time reduction, etc. The development process is briefly divided into several distinct phases, including standardization of biological reference material, 1,2 introduction of quality control, 3,4 establishment of standard operating procedures, 5,6 laboratory automation, and laboratory management