Precocene I and II are naturally occurring 2,2-dimethylchromenes that have a great influence on various insects. Using phenylboronic acid in acidic conditions, precocenes, natural products octandrenolone, clusiaphenone A, and relatives were prepared. In addition, the effects of synthetic chromene derivatives against Coptotermes formosanus Shiraki were evaluated in a no-choise test. The results demonstrate that they were able to induce antifeedant activities. It would seem that the precocene skeleton affects termites.

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