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A b s t r a c tFibrosarcoma is a malignant spindle cell tumor of the soft tissues uniformly composed of collagen-producing cells capable of exhibiting varying degrees of fibroblastic differenciation. This diagnosis was more liberally applied to many types of spindle and pleomorphic cell sarcomas that exhibited fibrosarcoma-like patterns, e.g., malignant schwannoma, synovial sarcoma, malignant fibrous histiocytoma, and some benign fibroproliferative lesions, particularly fibromatosis and reactive tumor-like lesions.The major challenge in the diagnosis lies in over and under diagnose of fibrosarcoma and underdiagnosis of reactive fibrosis. But this histologic differenciation is necessary owing to different treatment strategies.

Desmoplastic malignant melanoma is a rare variant of spindle cell melanoma commonly seen in older adults on sun-exposed areas. It accounts for 1–4 % of all cases of cutaneous melanoma. The common location of the desmoplastic melanoma is the head and neck region, whereasother sites are less common. A 45-year-old male presented with an proliferative growth on nose, after a trauma that was diagnosed as tumor. Histopathological examination with the help of wide panel of immunohistochemical methods and with emphasis on SOX10, was, after a broad diferential diagnosis concluded as a desmoplastic melanoma.

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or to rubber straps, which are sometimes used to fasten the ECG electrodes. DISCUSSIONOur patient showed a unique sensitization to PPD, a component of black rubber. To our knowledge, allergy to The allergic reactions that appear after ECG monitoring PPD, after ECG monitoring, has never been reported in the may be caused by ECG gels or pastes, alcohols found on literature. This unusual contact dermatitis, apparently not connected with ECG devices, occurred due to the particular composition of the electrodes made of rubber.