The combination of centhaquin 0.015 mg/kg and HES 130/0.4 resulted in shorter time to target MAP, lower wet-to-dry ratio, and better survival rates after resuscitation from hemorrhagic shock.

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Background. Since the first report of intrathecal opioids administration over 20 years ago the use of spinal opioids has become widespread. Co-administration of small doses of opioids and bupicavaine for spinal anaesthesia reduces intraopoerative discomfort and postoperative analgesic requirement in patients undergoing caeserean section Fentanyl, Morphine and Diamorphine (heroin) are the 3 common opioids in the UK.

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