This study aimed to investigate the relationship between cervical mucus viscosity and estrogen concentration, several blood biochemical profiles, and blood macro-mineral levels, as well as to determine the effect of cervical mucus viscosity and pH differences on pregnancy rates in Aceh cattle. Eight females Aceh cows aged 3-7 years old, with body weights of 150-250 kg were synchronized using a 25 mg single dose injection of PGF2α. Afterward, observation of estrus signs was performed for 30 minutes at 06:00 a.m. and at 06:00 p.m. Blood and cervical mucus samples were collected during the first cervical mucus secretion. The estrogen concentrations of each type of cervical mucus, namely thick, moderate, and thin were 29.39±6.29; 23.24±4.62; and 30.93 pg/mL, respectively. The pregnancy rate in cows with a cervical mucus pH of 6 and 9 was 0%. Meanwhile, the groups with a cervical mucus pH 7 and 8 had a pregnancy rate of 50%. An examination of cervical mucus showed different consistencies: five cows had mucus with a thick viscosity, with a 20% pregnancy rate; two had mucus with a moderate viscosity, with a 50% pregnancy rate and one had mucus with a thin viscosity, with a 100% pregnancy percentage. In conclusion, there is no significant relationship between estrogen concentration and cervical mucus viscosity levels in Aceh cattle. Levels of total protein, total cholesterol, and glucose were correlated to the viscosity of the cervical mucus. Higher levels of blood macrominerals (Na, K, Cl, Ca, P, and Mg) in female Aceh cattle resulted in greater viscosities of cervical mucus. The groups with cervical mucus pH of 7 and 8 had higher rates of pregnancy (50%) than the groups with cervical mucus pH of 6 and 9. The viscosity of cervical mucus also had an effect on the success of pregnancy in Aceh cattle.

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Moringa is widely known as a plant with high medicinal properties. Therefore, moringa has a high potential for use as an immunostimulant in shrimp. This study investigated the effect of a moringa water extract on the immune response, resistance against V. alginolyticus, and growth performance of whiteleg shrimp. To perform the in vitro assay, hemocytes were incubated with different concentrations of the moringa extract. Furthermore, the moringa extract was incorporated at 0 (control), 1.25 g (ME1.25), 2.5 g (ME2.5), and 5.0 g (ME5.0) per kg of diet for the in vivo assay. During the rearing period, immune responses, namely the total hemocyte count (THC), phenoloxidase (PO) activity, phagocytosis activity, superoxide anion production, and immune-related gene expression were examined on days 0, 1, 2, 4, 7, 14, 21, and 28. Growth performance was measured 60 days after the feeding period. Furthermore, the shrimp were challenged with V. alginolyticus after being fed for different feeding durations. The results of the in vitro assay revealed that 100–250 ppm of the moringa extract enhanced the PO activity, phagocytic rate (PR), and superoxide anion production. The findings of the in vivo assay demonstrated that the THC, PO activity, PR, and immune-related gene expression, including alpha-2-macroglobulin, prophenoloxidase II, penaeidin2, penaeidin3, anti-lipopolysaccharide factor, crustin, lysozyme, superoxide dismutase, and clotting protein, were higher in the group of ME.25 and ME5.0 than in the control and ME1.25 at several time points. Growth performance was significantly increased (p < 0.05) in the ME2.5 group compared to the control group. Furthermore, the dietary ME2.5 resulted in a higher survival rate compared to that of the control group after challenging with V. alginolyticus, especially at ME2.5 administered for 4 and 7 days. This study indicated that the incorporation of the moringa extract at 2.5 g per kg of diet enhanced the immune response, the growth performance of the whiteleg shrimp, and the resistance against V. alginolyticus infection.

Latar Belakang : Riset Kesehatan Dasar (Riskesdas) tahun 2013, pravalensi penyakit sendi berdasarkan diagnosa kesehatan di Indonesia 11,9% dan berdasarkan gejala 24,7%. Pravalensi berdasarkan diagnosis tenaga kesehatan tertinggi di bali 19,3% sedangkan berdasarkan gejala tertinggi di Nusa Tenggara Timur 33,1%, jawa barat 32,1%, DKI Jakarta 21,8% jika dilihat dari karakteristik umur , pravalensi tertinggi pada umur ≥ 75 tahun (54,8%) penderita wanita juga lebih banyak (27,5%) dibandingkan dengan pria (21,8%)(Riskesdas, 2013) Penelitian ini dilakukan di RSUD dr. H. Soewondo kendal pada bulan November 2017 dengan menggunakan sampel sebanyak 8 orang partisipan dengan metode quasi eksperimen jenis pretest-posttest. Tujuan : mengetahui pengaruh penggunaan Micro Wave Diathermy, Latihan aktif, Resisted active exercise dan Hold Relax pada osteoarthritis genu Hasil : uji normalitas data dengan saphiro-wilk test mendapatkan hasil distribusi data normal dengan nilai sig. untuk VAS sebelum terapi 0.168, VAS sesudah terapi 0.273, LGS sebelum terapi 0.592, LGS sesudah terapi 0.476, skor Jette sebelum terapi 0.507 dan skor Jette setelah terapi 0.501. uji hipotesis menggunakan paired sample t test didapatkan hasil berupa perubahan signifikan antara sebelum terapi dibandingkan dengan setelah terapi ditunjukan dengan sig. (2-tailed) untuk VAS 0,000, sig. (2-tailed) untuk LGS 0,001 dan sig. (2-tailed) untuk skor Jette 0,000. Kesimpulan : intervensi fisioterapi berupa Micro Wave Diathermy, Latihan aktif, Resisted active exercise dan Hold Relax terbukti mampu menurunkan derajat nyeri, meningkatkan lingkup gerak sendi dan Kemampuan fungsional aktivitas lutut partisipan.

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