The first rank of non communicable diseases in Jepara 2015 was 15,469 cases. The most cases are woman with 11,520 and men with 3,939. In Kalinyamatan health center 2015, there was an increase in hypertension cases from semester 1 until 2. Celery is plant that is easily found in the community, Celery contains apigenin which is very useful for preventing narrowing of blood vessels and high blood pressure. The purpose of this study was to determine the effect of celery juice on blood pressure reduction in hypertension patients. This research used quantitative method with quasy experiment approach. Data collection using random sampling techniques. The respondents of this study were 24 respondents. Data is collected in March - April 2019. Data analysis used non-parametric tests to measure significantly 2 groups of data paired with the T-Test. The results obtained an average decrease in systolic blood pressure of the diastol intervention group 0,000 and the control group 0.424. Moreover, the p-value is 0,000 <a (0,005). With a value of r systole -, 623 (strong closeness), r diastole -, 525 (moderate closeness). It can be concluded that there is a significant effect of celery juice on blood pressure reduction in hypertension patients in Jepara 2019.

Burn is heat transfer in which the source can be direct or indirect contact with fire, electricity, friction chemicals or radiation. It can cause damage of skin tissue even in a state of multisystem injury leading to serious disorders. Systemic effects and mortality caused by burn is generally determined by the extent and depth of affected skin. Cassava (Manihot esculenta Crantz) contains carbohydrates, phosphorus, calcium, vitamin C, vitamin B1, protein and iron. Furthermore, substances contained in cassava are able to give effect to the re-epithelialization of skin damaged cell tissue due to burns. The aim of this study was to find out the cassava tuber extract in gel preparation formulation and the effectiveness of burn healing in rabbits. This study was an experimental study to examine the concentration of cassava tuber extract gel formula which is the most effective in healing superficial burns of degree 4 in male rabbits. From the observations of giving gel preparations once a day by using positive control comparison (Bioplaceton) could be concluded that the extract of cassava provided healing which was not significantly different from the positive control.

Cervical cancer is the second leading cause of death for women in the world after breast cancer. It is estimated that every 40-45 new cases occur and around 20-25 people die due to cervical cancer. In Kudus , the coverage of early detection of cervical cancer by the VIA method is only 2% of the number of women aged 30-50 years. This study aims to determine the effectiveness of health promotion and guidebook on the early detection of cervical cancer as an effort to increase the participation in women's VIA examination. This study was quasiexperimental with the design of the pretest posttest non equvialent control, The samples as many as 66 respondents were divided into two groups selected taken using consecutive sampling technique. Later on, the data were analyzed using McNemar and Chi Square tests. The results showed McNemar test results in the intervention group found there was an increase in knowledge and participation in the VIA examination compared to the control group. Obtained differences between the intervention group and the control group using the Chi Square test with the p value of 0.003. Providing health promotion and guidebooks for early detection of cervical cancer are very effective in increasing the knowledge and women participation of VIA examinations in Mejobo Subdistrict, Kudus Regency.

The need for medicinal raw materials is increasing, in line with the increasing of traditional medicine utilization. Sangketan (Achyranthes aspera) is one of the potential medicinal plants, considering this plant contains active compounds that are beneficial for health. In an effort to increase productivity, quality, and continuity of medicinal plants, improvement in cultivation techniques is needed. The right use of growing media, will provide optimal environmental conditions for plant growth. Animal manure and rice husk charcoal are organic material, that can be used as a mixture of growing media. The purpose of this study was to determine the optimal combination of growing media, that could support the extract production from Sangketan. In Sangketan cultivation, given treatment at growing media composition of soil + rice husk charcoal, with comparison 1:1; 1:2 and 2:1. Whereas the fertigation uses goat manure fertilizer, with a concentration of 1 kg per 5 liters of water, dose of 60 ml per plant every two weeks. Sangketan is harvested after 4-5 months, then quantitative analysis is performed of resulting extracts. The research data was applied using simplex lattice design (SLD), to obtain the optimal combination of growing media. Sangketan resulting extracts was applied using SLD, obtained the equation Y = 8.94 (Charcoal) + 11.585 (Soil) + 14.26 (Charcoal.Soil). Results of this study can identify and evaluate, technologies that support the sangketan development as a raw material for traditional medicine.

The need for medicinal raw materials is increasing, in line with the increasing of traditional medicine utilization. Sangketan (Achyranthes aspera) is one of the potential medicinal plants, considering this plant contains active compounds that are beneficial for health. Triterpenoids are one of the main secondary metabolites of Sangketan. The purpose of this study was to determine the optimal combination of growing media, that could support the extract production from Sangketan. In Sangketan cultivation, given treatment at growing media composition of soil + rice husk charcoal, with comparison 1:1; 1:2 and 2:1. Whereas the fertigation uses goat manure fertilizer, with a concentration of 1 kg per 5 liters of water, dose of 60 ml per plant every two weeks. Sangketan is harvested after 4-5 months, then qualitative analysis is performed of resulting extracts. The research data was applied using simplex lattice design (SLD), to obtain the optimal combination of growing media. Qualitative data of Sangketan extract containing triterpenoid compounds, have been analyzed by chloroform and concentrated H2SO4 reagents, characterized by a reddish brown layer. Sangketan resulting extracts was applied using SLD, obtained the equation Y = 8.94 (Charcoal) + 11.585 (Soil) + 14.26 (Charcoal.Soil). The triterpenoid compound in Sangketan extract was proven using thin layer chromatography, showed marker compounds in form of gray spot under UV light 254 nm at Rf value 0.65.