Ivermectin drug used in the treatment of endo and ecto parasites in animals, but in this study was used to treat Bovine ocularsquamous cell carcinoma (BOSCC) at a dose 200 mg /Kg body weight. Forty cattle were used in this study in a period from January 2014 to December 2015. The result of this study was revealed significant increase (P≤0.05) in the mean of total white blood cells count (5.39 ± 1.052) cell/mm 3 before treatment and reach to (6.49 ± 0.422)cell/mm 3 after treatment and the mean of lymphocyte rate (34.5 ± 3.20)% before treatment and reach to (60.6±10.83)% after treatment. Also, there was significant depression (P≤0.05) in the means of neutrophils and monocytes rates (59.4 ±4.52)% , (4.3 ±1.40)% before treatment compare with percentage of cells after treatment were (34.4 ±9.56)% , (2.2 ± 1.15)% respectively. The result showed significant (P≤0.05) decreased in the TNF-Alpha level (10.1 ± 1.1) ng/L in after treatment, while was (14.9 ± 0.48) ng/L before treatment compare with the control group was (6.5 ± 3.1) ng/L. Sixteen cattle were recovering from sum of twenty cattle in the treated group, the cure rate reaches to 80% with sign of loss the cancer mass size without any side effect on the animals. The Ivermectin could be a drug to treat BOSCC with a 80% cure rate.
This study was conducted to evaluate the effect of Ocimum Basilicum seeds supplementation of a commercial broiler diet on the performance and immune response. Three dietary treatments(100 birds/treatment) with two replicates (50 birds/ replicate) one day old straight run Ross 308 . T1 (as control group) birds fed basal diet without any additives. While, T2 and T3 fed diet supplemented daily with 0.3 and 0.6% basil seeds respectively to the end of the experiment (42 days) to investigate the broiler performance and antibody titer against Newcastle disease virus (NDV) and infectious bronchitis (IB). Results showed that the two levels of Ocimum Basilicum seeds supplementation (0.3 and 0.6%) had a beneficial effect on the antibody titer against (NDV) and (IB) and the high level (0.6%) was more significant against (NDV) while the low level (0.3%) was more significant against (IB). The high levels of antibodies titers were considered as the indicative of antiviral activity of O. Basilicum seeds. in addition, The results revealed significant (p<0.05) improvement of feed conversion ratio and high liver weight and spleen index in treatment groups compared with control group. In conclusion, Ocimum Basilicum seeds supplementation in commercial broiler diets was beneficial to broiler performance and immune function.
In order to determine the fungi that association with ocular infections of bovine in Diyala/ Iraq. Eighty samples were collected from bovine which shows clinical signs of inflammation of the eye in the calves and cows are profuse Altadma, watery, serous and purulent thick secretions of the eye, swelling eyelids, adhesion eyelashes, keratitis with Keratohelcosis, congivetitis keratitis, emaciation and weakness. These samples were collected during four months, which began in January 2018 till April, from several areas of Baqubah city these samples were collected by sterile cotton swabs from the eyes and conjunctiva sac. The results showed that (45%) bovine samples were positive fungal isolation. The result showed higher percentage of fungal isolated in February(30%) followed by January(35%), March(25%) and April showed lower percentages of fungal isolates(10%).The current results explained that most of eye infections were unilateral (80%) while the bilateral were (20%). In conclusions, the fungus is one of the most important reasons that lead to eye infection and inflammation. The main fungal species that isolated were Aspergillus spp.(50%), followed by Mucorales also isolated (22.3%) then Candida spp. (16.6%), as well as the lower percentage of Alterneria spp. (11.1%).
| This study was carried out to find the pathological changes on mice infected experimentally with Absidia spp isolated from cats, and immune modulator effects of β-glucan compound against Absidia spp. To achieve the goal, Forty mice were divided randomly into two groups, 1 st group (n=20 mice) fed on diet supplement with 100mg/kg diet of β-glucan for 5weeks. 2 nd group (n=20 mice) was served as a control group. The two groups were challenged with 1×10 7 fungal cells/ml I/P of virulent Absidia spp. The result showed that 5out of 20 mice in the first group died at 1-3 days and 14 out of 20 mice in the second group. The level of protection observed in the mice of the first group showed in 75% of infected immunized mice, where 30% protection was reported in mice of the second group. The histopathological examination in the control group of mice showed acute suppurative inflammation in the examined organs at 24-72 hour post infection with necrosis, inflammatory cells infiltration and the mold and hyphae were observed in the liver, kidney, spleen and lung, as well as moderate to mild pathological lesion at day 45 post-inoculation, Mononuclear cells and neutrophils were seen in most examined organs of the 1st group. The present study was concluded that the Absidia spp. causes high pathological lesions and the β-glucan as immunomodulater alone provided partial protective immunity against lethal doses of Absidia spp. Histopathological Study and Effect of Β-Glucan asImmunomodulater in Mice Infected by Absidia spp. citation | Alkhalidi AA, Aljumaily S, Taher MG, Mohammed ZI (2019). Histopathological study and effect of β-glucan as immunomodulater in mice infected by absidia spp. Adv. Anim. Vet. Sci. 7(6): 508-515. doI | http://dx.
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