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PurposeHigh blood pressure (hypertension) is a relatively common condition that increases blood pressure in the arteries abnormally, causing problems such as heart disease and stroke. Blood pressure is a force that is felt through the walls of the blood vessels and has a direct relationship to the power of pumping the heart and vascular resistance to the blood flow. One of the lowing of blood pressure medications is hydrochlorothiazide (Hctz) which is used to treat high blood pressure and swelling from heart failure, liver damage, and other minor actions.ProceduresThis study explains the effectiveness of Hctz with the help of “fractal dimension”. To perfect investigate the fractal dimension, we used the Hctz drug nanoparticle form then using MATLAB software, homogeneity levels or heterogeneity of Nano Hctz using SEM images were computed.ResultsWe calculated histogram plot with SEM image by MATLAB software which that its standard deviation was eclose to zero and it can explain that the scattering of data is low and their amount is in one suffering. Fractal dimensions obtained from Matlab and SPSS software for normal distribution, correlation, standard deviation, mean, cumulative frequency and variance analysis were analyzed.ConclusionsIn this research, the association between Hctz treatment effects with the point of view of the fractal dimension of the drug was demonstrated to prove the properties of the drug in the body. in the near future, drug fractal studies can improve the development of new drugs and treatments with minimal cost than clinical approaches by linking chemistry, mathematical sciences and pharmaceutical sciences.

Some arsenic compounds can show extraordinary polymorphism. Realgar (As 4 S 4 ) is among several minerals with various crystal forms and is one of the most important sources of arsenic for pharmaceutical use. Currently, realgar is used as an arsenic source in many industries, such as weaponry, publishing, textiles, cosmetics, and health products. In this paper, we used and reported new methods for the purification, nanonization, and structural morphological investigations of As 4 S 4 by using planetary ball mills process for nanonization of the compound. The product was characterized using X-ray powder diffraction analysis, Fourier transform infrared spectrometry spectra, and field emission scanning electron microscope (FESEM) imaging. We investigated the morphological properties of FESEM-imaged realgar nanoparticles by an image-processing technique that calculates fractal dimensions using values on a computer with MATLAB software. We applied the Statistical Package for the Social Sciences software for statistics data extracted from the FESEM image and obtained the statistics results of the fractal dimension and histogram plot for the FESEM image.

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