Fiber-affecting diseases - encompassing fibrosis, heart disease, neurological disease and cancer - are directly linked to the density and reorganization of fibrous media in biological tissue. Polarized light has unique...

We leverage the unique properties of anisotropic, colorimetric metasurfaces to selectively visualize disease-relevant fiber density and orientation in biological tissue, paving the way toward rapid, precise and low-cost diagnostics ranging from cancer to neurodegenerative disease.