Background: Treatment of either physical or mental illnesses is not as effective if the knowledge and awareness of the patient is inadequate. Study design: Descriptive study. Methodology: A total number of 240 students through convenient sampling who responded to the questionnaire. The ethical approval was obtained from review ethical committee, after completing and submitting the research proposal. The research instrument for data collection was, “structured questionnaire” developed by using 2 scales, the mental health literacy scale (MHLS) and modified scale. Data was analyzed by SPSS version 23. Chi-square test was applied for categorical variables to find the differences in knowledge and practices by dental professionals with p-value ≤0.05 as significant. Results: Almost 86.7% of students were able to identify major depressive disorder.8.3% thought such disorders are punishment by God, 38.3% of students considered mental illness as inherited trait. According to 47.5% treatment of mental illness caused addiction, 37.1% were unsure and 15.4% disagreed. Practical Implication: This study helped researchers in exploring role of multiple factors in changing mental health literacy and how it can help in reducing those barriers and promoting mental health literacy in students. This also added to local literature regarding mental health. Conclusion: It was concluded that mental illness needs recognition and awareness campaigns for mental health literacy needs to be conducted. Keywords: Mental Health, Knowledge, Awareness, Attitude and Individual Performance.

Background: According to international society of nephrology about 2 million people die with AKI every year. Elder patients and pediatrics have less immunity due to which concurrent administration of medication may damage the nephrons. Aim: To evaluate the effect of glucocorticoids on serum total protein level in control and experimental groups induced by nephrotoxic poison Concanavalin-A. Methodology: This experimental study was conducted at Agriculture University of Faisalabad-Pakistan following approval from ethical committee. Subject animals (n=12) were equally divided into 3 groups, 1st was control group, 2nd was treated group and 3rd was untreated group. The collected data was analyzed by using SPSS version 20. ANOVA ware applied with P-value< 0.05 Results: It was found that analysis of serum protein levels showed significant increase in total protein and globulin in Con-A induced toxic group as compare to control group. Conclusion: It was concluded that dexamethasone treated group showed significant reduction in total protein level and globulin level. Results of serum albumin level were non-significant. Most important of all is serum A/G ratio which showed significant results. Significant reduction in serum A/G ratio in dexa treated group in comparison to untreated group thus dexamethasone was nephro-protective. Keywords: Glucocorticoids, Serum Protein Markers and Concanavalin-A.

Background: According to international society of nephrology about 2 million people die with AKI every year. Aim: To evaluate the effect of GR ligands on renal functions of mice induced by nephrotoxic poison Concanavalin-A. Study design: Experimental study. Methodology: The study was conducted at Agriculture University of Faisalabad-Pakistan following approval from ethical committee. Mice having age around 10 weeks, weighing 25 to 30 grams, kept under observation at animal house facility at University of Agriculture for 9 days. Subject animals (n=12) were equally divided into 3 groups, 1st was control group, 2nd was treated group and 3rd was untreated group. Renal markers, creatinine, urea and BUN were estimated from blood sample by using serum analyzer. The collected data was analyzed by using SPSS version 20. ANOVA ware applied with P-value< 0.05 as significant. Results: Analysis of kidney function test showed significance increase in creatinine, urea and BUN level in Con-A induced toxic group. They were normalized in pretreated groups receiving GR ligand (Dexa). Conclusion: It was concluded that glucocorticoids ameliorated the Con-A induced nephrotoxicity by significantly reducing the elevated kidney biomarker levels including creatinine, urea and BUN in mice serum. Keywords: Glucocorticoids, Serum Urea, BUN and Concanavalin-A.