BaNd2Ti3O10 has been considered as a promising thermal barrier coating (TBC) candidate material, which reveals many advantages over the widely used TBC material of yttria partially stabilized zirconia, such as lower thermal conductivity, better high-temperature capability, and higher resistance to environmental deposits corrosion. In this study, the hot corrosion behavior of BaNd2Ti3O10 in Na2SO4 + V2O5 molten salt at 900 °C and 1000 °C is investigated. Exposed to the salt for 4 h at 900 °C, BaNd2Ti3O10 pellets had an obvious reaction with the salt, forming corrosion products of NdVO4, TiO2, and BaSO4, and the reaction layer was ~30 μm, beneath which no salt trace could be found. Prolonging the corrosion time to 20 h, the type of the corrosion products had no change. At an elevated corrosion temperature of 1000 °C for 4 h, the corrosion products were still NdVO4, TiO2, and BaSO4, but NdVO4 revealed a significant growth, which fully covered the pellet surface. The mechanisms by which the corrosion reaction between BaNd2Ti3O10 and the molten salt occurred were discussed.