Mycotic aneurysms constitute a small proportion of aortic aneurysms. Endovascular repair of mycotic aneurysms has been applied with good short-term and midterm results. However, the uncommon aortoenteric fistula formation remains a potentially fatal complication when repairing such infective aneurysms. We present the case of an 80-year-old woman with thoracic and abdominal aortic mycotic aneurysms, which were successfully treated with endografting. However, the patient presented 3 months later with upper gastrointestinal bleeding secondary to erosion of the thoracic graft into the oesophagus. The patient was treated conservatively due to the high risk of surgical repair. There is currently little exposure to the management of mycotic aortic aneurysms. If suspected, imaging of the entire vasculature will aid initial diagnosis and highlight the extent of the disease process, allowing for efficient management. Aortic endografting for mycotic thoracic aneurysms is a high-risk procedure yet is still an appropriate intervention. Aortoenteric fistulae pose a rare but severe complication of aortic endografting in this setting.
Objective: The objective of the study was to establish the efficacy and tolerability of oral Unani formulations with inhalation of Kalonji and to provide safe, effective, and economical treatment for Iltehab Tajaweefe Anaf Muzmin (chronic rhinosinusitis [CRS]). Methods: A randomized single-blind, comparative study of 40 patients of CRS. The patients were randomly allocated to two groups each consisting of 20 patients. In Group A, oral Unani formulation of Katan (Linum usitatissimum), Filfil Siyah (Piper nigrum), and honey was given 6 g BD with steam inhalation of Kalonji (Nigella sativa) and Tab Alaspan 1 BD with Karvol Plus inhalation was given in Group B. Results: Statistical analysis of the data was done using paired t test by comparing the visual analog scale score of all major and minor symptoms before and after treatment. The result is statistically highly significant in Group A (p<0.0001) and it is significant in Group B. (p<0.01). Conclusion: It may be concluded that the oral Unani formulation with inhalation of Kalonji has statistically highly significant effect on major and minor symptoms of CRS. A multicentric trial of the test drug on larger sample size for a longer duration is required to establish the efficacy of the formulation on CRS.
In Sanskrit it is called as Bshpika, Kalajaji, karavi, Kunchi, Kunchika, Kunjika Musavi, Sthulajarika, Upakuncharika, Sushavi, Krishna-jiraka, Upakunchika. In Unani its name is Kalonji, Shoniz and in Urdu it is called as Kalonji.
Meniere’s disease, also called endolymphatic hydrops, is a disorder of the inner ear where the endolymphatic system is distended due to endolymph. It is characterized by vertigo, Tinnitus, sensorineural hearing loss and aural fullness. The main pathology in Meniere’s disease is distention of endolymphatic system due to increased volume of endolymph. This can result either from increased production of endolymph or its faulty absorption or both. The description of hypothyroidism as a disease is not directly found in Unani texts. However, the signs and symptoms of meniere’s disease such as Dawar (vertigo), Taneen (tinnitus), Hissi Asabi Bahrapan (sensorineural hearing loss), Seqal-e-Uzn (aural fullness) mentioned in unani medicine associated with clinical manifestation in the context of Su-e-Mizaj Barid Maddi (derangement in cold temperament) as a result of an excess production endolymph (Kasrate Ifraz-e-Androon lymph) or defective absorption of endolymph (Nuqse Jazb-e- Androon lymph) in abnormal phlegm in the internal ear. On the basis of this fact, an attempt has been herewith made to understand the disease and its management through Unani Medicine. Keywords: Meniere’s disease, Vertigo, Tinnitus, Taneen, Deafness
More than 54 million Americans suffer from some form of arthritis and 23.7 million are limited in their usual activity, primarily due to pain. The study aims to highlight the concept of Arthralgia and the potential of its management in Unani Medicines. Osteoarthritis (OA) is a slowly progressive condition with a variable prognosis. In general, predicting the prognosis in patients with OA is difficult. However, pharmacological therapy can be associated with serious side effects and high costs. Therefore, alternative therapies have been under investigation. Herbal medications have shown the potential for safe and effective management of arthritis. The Unani Medicine is a rich source of classical knowledge on arthritis. OA has been mentioned as Wajaul Mafasil Balghami/Saudawi, and Unani Physicians has been treating this disease successfully with mostly single herbal drugs and their compound formulations for centuries. It has been revealed through animal, in vitro, and clinical studies that most of the single and compound Unani formulations are safe, without any side effects, and effective in OA, especially gout and rheumatoid arthritis. There is a need to conduct studies at Phase III level after analyzing 2nd Phase clinical studies of Unani medicine, so a promising safe, economic, and effective treatment can be provided to the ailing society for OA.
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