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With this in mind, multiple vaccination strategies are currently pursued targeting the S protein as an ideal candidate protein that may elicit cross-protective immunity (Table 1). Additionally, as a therapeutic option, a broadly acting cocktail of repurposing drugs might be the most pragmatic strategy to combat COVID-19. 12 Drugs targeting the replication steps of the virus, 12 and therapeutics alleviating the observed cytokine storm and hyperinflammation reducing acute lung injury would help patients. Interestingly, off-label treatment with the IL-6 blocker tocilizumab has been described in Giamarellos-Bourboulis et al, 1 and several immunosuppressive drugs evaluated or approved for rheumatoid arthritis are currently assessed in clinical trials for COVID-19 patients.

Frequent consumption of cereals, rice, pasta and chocolates may have beneficial effect on symptoms of rhinoconjunctivitis. Although dietary habits may affect the prevalence of symptoms of current rhinoconjunctivitis, the Mediterranean diet alone may not be protective against rhinoconjunctivitis.

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