The 150‐km seismic gap in the Sea of Marmara is the longest section of the North Anatolian Fault that has not ruptured in the last century. Recent geodetic studies suggest that the interseismic coupling along the Main Marmara Fault (MMF) is heterogeneous with locked and creeping segments. Alternatively, the MMF is fully locked, but the strain is localized asymmetrically around the fault due to the deep basins. In this study, we build a 3‐D model of the region, including the basins and the 3‐D fault geometry, to study the competing effects of deep basins and the interseismic locking distribution using the observed Global Navigation Satellite System velocities. We conclude that the basins along the fault localize the interseismic strain, leading to slightly deeper‐estimated locking depths. The on‐land data are too far to constrain the full interseismic coupling, especially in the Central Marmara. The Western Marmara is better resolved, where we infer a ∼50‐km creeping zone. The transition from the creeping to the locked behavior in Western Marmara is around the Ganos Bend. The creeping zone correlates well with a higher rate of diffuse seismicity and repeating earthquakes, implying that the seismicity could be an indicator of interseismic behavior. Variations of earthquake focal mechanisms and associated regional stresses are also consistent with compressional and dilatational quadrants due to the creeping segment. The significant thrust components observed in the 2019 Silivri earthquake sequence north of the MMF can also be explained by the compressional loading due to the interseismic creep further west.

Objective: Malignant lymphoma is one of the most common cancer type around the world. In this study, the distribution and demographic characteristics of the histologic subgroups of mature lymphoid neoplasms in Northeast Turkey were investigated. Methods: The study consists of 1136 patients diagnosed as mature lymphoid neoplasm between 2008 and 2014. The demographic data of the patients were analyzed and histological subgrouping was performed according to the World Health Organization classification.Results: Mature B-cell neoplasms accounted for 79.2% (n=900) of all lymphoid neoplasms, Hodgkin lymphoma (HL) for 10.9% (n=124), mature T/natural killer-cell neoplasms for 9% (n=102), and histiocytic and dendritic cell neoplasms for 0.9% (n=10). In our study, the most common subtypes of lymphoid neoplasms were as follows: diffuse large B-cell lymphoma (n=261; 23%), plasma cell myeloma (n=252; 22.2%), chronic lymphocytic leukemia/small lymphocytic lymphoma (n=230; 20.2%), mycosis fungoides (MF) (n=66; 5.8%) and nodular sclerosing type classical HL (n=63; 5.5%). Only 2.9% of the cases of non-Hodgkin lymphoma (NHL) were follicular lymphoma. All patients with HL were diagnosed by a lymph node biopsy. However, 48.1% of the patients with NHL arose from extranodal sites. Conclusions: This is the first study investigating the distribution of lymphoid neoplasms in Northeast Anatolia region with the review of the literature. The present study showed that the epidemiologic features similar to those reported in Western and Asian countries, whereas some subtypes showed distinct features. The high frequency of MF and the low frequency of follicular lymphoma are interesting findings of this study.

In the first two parts of the study, the literature review and in the third part, the cartoon Pepee and Masha and the Bear was examined by using the embedded theory method, one of the qualitative research methods. The theoretical sampling method, one of the purposive sampling methods, was used in the selection of the sample. The sample of the research consists of ten episodes of Pepee cartoon and ten episodes of Masha and the Bear cartoon. The document analysis method was used in the analysis of the cartoon Masha and the Bear, which was watched on the Turkish youtube channel, Pepee and Masha and the Bear. As a result of the analyzes, when the verbal expression and behavioral expression dimensions of the values in the Pepee cartoon were compared, it was determined that they were presented to the audience as verbal expression categories rather than behavioral expression value categories. Of the total value expressions (n= 457), 372 were in the "verbal expression dimension" and 55 were in the "behavioral expression dimension". When the verbal expression and behavioral expression dimensions of the values in the cartoon Masha and the Bear were compared, it was determined that they were presented to the audience as behavioral expression categories rather than verbal expression value categories. Of the total value expressions (n= 168), 112 were in the "behavioral expression dimension" and 56 in the "verbal expression dimension".

ÖZETAmaç: Papüler akantolitik diskeratozis nadir görülen kronik bir deri hastalığı ve klinikopatolojik bir antitedir. Genelde anogenital ve genitokrural bölgede cilt renginde veya beyazımsı papüller şeklinde kendini gösterir. Genç kadınlarda vulvada persistan papüler lezyon olarak klinik bulgu verir. Persistan olmasına rağmen asemptomatiktir.Olgu: 62 yaşında kadın hastada sağ labium majus lateralinde yaklaşık 0,3 cm çaplı büllöz karakterde tek bir lezyon izlendi. Histopatolojik incelemede hiperkeratoz ve akantoz yanı sıra akantoliz ve 'corps rond' ve 'grain' tipinde diskeratotik hücreler tespit edildi. Histopatolojik ve klinik bulgular eşliğinde olguya papüler akantolitik diskeratozis tanısı verildi.Sonuç: Ayırıcı tanıda Hailey-Hailey ve Darier hastalığı başta olmak üzere verrüköz diskeratom ve Grover hastalığı yer almaktadır. Lezyonun klinik olarak özellikleri, lokalize veya yaygın oluşu, aile öyküsü ve genetik mutasyonlar ayırıcı tanıda önemlidir.Anahtar Sözcükler: Diskeratozis, Anogenital, Genitokrural, Papüler akantolitik diskeratozis ABSTRACT Aim: Papular acantholytic dyskeratosis is a rare, chronic skin disorder and clinicopathological entity. It usually manifests with skin-colored or whitish papules on the anogenital and genitocrural area. Clinically, this disease presents as a persistent papular lesion on the vulva of young women. Despite being persistent, it is asymptomatic. Case:A 62-year-old female patient was found to have a 0,3 cm single, bullous lesion over the right labium majus. Histopathological examination revealed hyperkeratosis and acanthosis as well as acantholysis and dyskeratotic cells forming corps rond and grains. Papular acantholytic dyskeratosis was diagnosed with histopathological and clinical findings. Conclusion:Differential diagnosis includes mainly Hailey-Hailey and Darier's diseases as well as verrucous dyskeratoma and Grover's disease. Clinical features of the lesion, presents in a localized or generalized form, family history and genetic mutations are important in differential diagnosis.