The Ten-Item Personality Inventory (TIPI) was designed as a brief instrument of the Big Five personality traits. This study aimed to explore the internal consistency and structural validity of the Chinese version of TIPI (TIPI-C) in medical college students. Methods: A cross-sectional study was conducted in 11 provinces of China. Spearman-Brown coefficient, standardized Cronbach's α coefficient, and Cronbach's α coefficient were applied to estimate the internal consistency. Spearman-Brown coefficient was applied to estimate split-half reliability. Principal components analysis (PCA) and confirmatory factor analysis (CFA) were used to identify the structural validity. Results: A total of 2223 medical college students recruited from different regions of China were included. The Spearman-Brown coefficients of TIPI-C ranged from 0.129 to 0.786 and the Cronbach's α coefficients ranged from 0.119 to 0.785. The split-half reliability of the Spearman-Brown coefficient was 0.508. The latent structure of Extraversion, Emotional Stability, and Conscientiousness complied with the intended structure, and the internal consistency coefficients of these three traits were supported. However, the internal consistency coefficients of Agreeableness and Openness were low and the structural validity was not supported. Conclusion: TIPI-C primarily stands out as a feasible instrument for brief measurements of the Extraversion, Emotional Stability, and Conscientiousness domains. Further research is required to evaluate the concurrent validity and the test-retest reliability of TIPI-C in different populations and potentially modify the instrument to be more suitable for the Chinese population.

No abstract

Background Infertility and its treatment have negative impacts on a couple’s marital relationship, sexual life, psychological state and interpersonal relationships, causing personal distress. Health-related quality of life (HRQoL) has become an important component of health outcomes. HRQoL instruments developed in western culture are not always appropriate for use in China due to cultural differences. Probably due to the unique concept of fertility in China, infertility patients can be looked down upon and the family may  feel shameful. This study aims to develop a HRQoL instrument for infertile couples based on the Chinese social and cultural setting. Methods Complementary mixed methods will be used to develop a new HRQoL instrument for Chinese infertile couples. The study consists of four stages: the first stage will involve a systematic review and qualitative interviews to construct draft candidate items. In the second stage, quantitative research [e.g., exploratory factor analysis (EFA), item response theory (IRT)] and cognitive interviews will be used for item selection. The third stage will be instrument validation, in which classical test theory (CTT) and IRT will be applied. In the final stage, the minimal clinically important difference (MCID) will be calculated by using distribution-based methods and anchor-based methods (e.g., logistic regression, receiver operating characteristic curve). Discussion The new HRQoL instrument for Chinese infertile couples will be developed, which will provide a standard and effective HRQoL instrument in clinical outcome assessment and health outcome measurement.

Purpose To investigate the health-related quality of life (HRQoL) and subjective well-being (SWB) of children aged 9–12 years in eastern China, and examine concordance within parent-child dyads. Methods Data was collected from 9–12 years students (including their parents) in Shandong Province in 2018. Participants self-completed a hard-copy questionnaire including Child Health Utility 9 Dimension instrument (CHU9D), Pediatric Quality of Life Inventory (PedsQL)™ 4.0 Short Form 15 Generic Core Scales (hereafter the PedsQL), Student’s Life Satisfaction Scale (SLSS), as well as information on socio-demographic characteristics and self-report health status. Spearman’s correlation coefficients and the difference between sub-groups were conducted to assess and compare the agreement on HRQoL and SWB instruments. The concordance of within parent-child was analyzed using Cohen’s kappa coefficient and Bland-Altman plots. Results A total of 810 students and 810 parents were invited to participate in the survey. A valid sample of 799 (98.6%) students and 643 (79.4%) parents completed the questionnaire. Students’ mean self-reported CHU9D/PedsQL/SLSS scores were 0.87/83.48/30.90, respectively. The parent proxy’s PedsQL and SLSS scores were 68.61 and 31.23, respectively. The CHU9D was moderately correlated with the PedsQL (r = 0.52). There was a weak correlation between CHU9D and SLSS (r = 0.27). A low level of concordance was observed across all comparisons and in all domains (kappa < 0.20) between parents and their children. Besides, a high level of disagreement was observed between children’s own and fathers’ assessment. Conclusions CHU9D and PedsQL instruments have a higher agreement in measuring the HRQoL in children. CHU9D/PedsQL and SLSS instruments showed a low agreement and this suggests that measuring SWB in children potentially may provide further information that might be overlooked by using HRQoL instruments exclusively. Concordance between parents and children was poor. Overall, mothers-children dyads showed a higher concordance than fathers-children dyads.

Objectives This study aimed to evaluate health state utility (HSU) and compare the health-related quality of life (HRQoL) among elderly people in northwest China, and explore the factors affecting the HRQoL Methods In 2021, 1500 elderly were randomly recruited in Lanzhou, Gansu Province, the EQ-5D-5L and 15D scales were used to measure HRQoL and HSU. Descriptive analyses, such as demographic characteristics, socioeconomic status, etc. And the Tobit regression and multiple linear regression models were used to evaluate the related factors of HSU. Result A total of 1,320 older adults completed the study, and 35.3% elderly were normal weight; overweight elderly were 445(33.7%); obese elderly were 409 (31%). These elderly’s HSU was 0.941, 0.930, and 0.909 in the EQ-5D-5L, and in the 15D scale were 0.872, 0.858, and 0.845. Those aged 65–70, 70–75, 75–80 and above 80 HSU were 0.93, 0.927, 0.920 and 0.882 in the EQ-5D scale ( 0.867, 0.857, 0.850, and 0.837 in 15D). Males and females HSU were 0.939 and 0.918 ( 0.879 and 0.844 in 15D). Subgroup analysis, Tobit regression, and multiple linear regression showed that BMI, gender, age, marital status, and previous medical history were all related to the HRQoL of the elderly. Conclusion The EQ-5D-5L and 15D scales were used to measure the HSU of elderly people in northwest China and found overweight or obese, female, older age, marital status, and previous medical history. were closely associated with impaired HRQoL in the elderly.