No abstract

40 •nH 2 O in aqueous solution, and characterized by elemental analysis, IR spectra and DTA-TG-DTG techniques. The IR spectrum confirmed the presence of Keggin structure and the characteristic functional group for ciprofloxacin in the compound. The TG-DTA-DTG curves showed that its thermal decomposition was a four-step process consisting of simultaneous collapse of Keggin type structure. The residue of decomposition was the mixture of WO 3 and SiO 2 , confirmed by X-ray diffraction and IR spectroscopy. The decomposition mechanism and nonisothermal kinetic parameters of the polyoxometalate were obtained from an analysis to the TG-DTG curves by the single scanning methods (the Achar method and Coats-Redfern method) and the multiple scanning methods (the Kissinger method, Flynn-Wall-Ozawa method and Starink method

In the title compound, C19H20ClN3O2S, the two fused rings of the thieno[2,3-d]pyrimidin-4(3H)-one system are almost coplanar. The packing of the molecules in the crystal structure is mainly governed by intermolecular C—H...O hydrogen-bonding and π–π interactions.

Background The relationship between fibrosis-4 (FIB-4) index and clinical outcomes in patients with acute kidney injury (AKI) is unclear. We aimed to investigate the association between FIB-4 index and all-cause mortality in critically ill patients with AKI. Methods We used data from the Multiparameter Intelligent Monitoring in Intensive Care III (MIMIC-III) database (v1.4). The FIB-4 score was calculated using the existing formulas. logistic regression model, and Cox proportional hazards model were used to assessed the relationship between the FIB-4 index and in-hospital,28-day and 90-day mortality, respectively. Results A total of 3592 patients with AKI included in the data analysis. 395 (10.99%) patients died during hospitalization and 458 (12.74%) patients died in 28-day. During the 90-day follow-up, 893 (22.54%) patients were dead. An elevated FIB-4 value was significantly associated with increased in-hospital mortality when used as a continuous variable (odds ratio [OR] 1.183, 95% confidence interval [CI] 1.072–1.305, P = 0.002) and as a quartile variable (OR of Q2 to Q4 1.216–1.744, with Q1 as reference). FIB-4 was positively associated with 28-day mortality of AKI patients with hazard ratio (HR) of 1.097 (95% CI 1.008, 1.194) and 1.098 (95% 1.032, 1.167) for 90-day mortality, respectively. Conclusion This study demonstrated the FIB-4 index is associated with clinical outcomes in critically ill patients with acute kidney injury.

The polyoxometalate (CPFX·HCl) 3 H 3 PW 12 O 40 ·8H 2 O was prepared and characterized by elemental analysis, IR spectra and TG-DTA-DTG. The thermal decomposition mechanism and non-isothermal kinetic parameters of the polyoxometalate were obtained from the analysis of TG-DTG data using the Achar equation, Coats-Redfern equation (CR), Madhusudanan-Krishnan-Ninan equation (MKN) and HorowitzMetzger equation (HM). And their mathematical expressions of the kinetic compensation effect were also calculated.