Multi-channel Virtual reality simulation technology is a kind of simulation technology, which support the grand scene and high degree of immersion, has better visualization effect. In this paper, a moving target monitoring collaboratory simulation technology based on multi-channel is studied. Firstly, study the mathematical modeling foundation of Multi-Channel technology systematically, based on the mobile target spatial model and co-simulation technology, select the appropriate applications of multi-channel technology, building laboratory simulation platform and achieved a space-based six-degree of freedom simulation of multi-channel moving target monitoring simulation. The experiment has proved that in multi-channel target monitoring co-simulation technology used in this paper has strong practicality, combine with a moving target-space model and co-simulation technology, the advantages of objective observation to solve the requirements like large-scale, realism, immersion requirements, etc.