The novel COVID-19 outbreak has affected more than 200 countries and territories as of March 2020. Given that patients with cancer are generally more vulnerable to infections, systematic analysis of diverse cohorts of patients with cancer affected by COVID-19 is needed. We performed a multicenter study including 105 patients with cancer and 536 age-matched noncancer patients confirmed with COVID-19. Our results showed COVID-19 patients with cancer had higher risks in all severe outcomes. Patients with hematologic cancer, lung cancer, or with metastatic cancer (stage IV) had the highest frequency of severe events. Patients with nonmetastatic cancer experienced similar frequencies of severe conditions to those observed in patients without cancer. Patients who received surgery had higher risks of having severe events, whereas patients who underwent only radiotherapy did not demonstrate significant differences in severe events when compared with patients without cancer. These findings indicate that patients with cancer appear more vulnerable to SARS-COV-2 outbreak.SIgnIfICAnCe: Because this is the first large cohort study on this topic, our report will provide muchneeded information that will benefit patients with cancer globally. As such, we believe it is extremely important that our study be disseminated widely to alert clinicians and patients.

The electrochemical behavior of a lithium/sulfur (Li/S) battery was studied by electrochemical impedance spectroscopy (EIS). An impedance model based on the analysis of EIS spectra as a function of temperature and depth of discharge was developed. Then, by monitoring the evolution of impedance during the cycling process, the capacity fading mechanism of Li/S battery was investigated. The results show that the semicircle at the middle frequency of the EIS spectra is ascribed to the charge-transfer process and the semicircle at high frequency is related to the interphase contact resistance. Furthermore, electrolyte resistance, interphase contact resistance, and charge-transfer resistance vary with cycle number in different manners, and the charge-transfer resistance is the key factor contributing to the capacity fading of Li/S battery.

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