No abstract

Gold takes to water: The synthesis of amides directly from alcohols and amines was realized by using a water‐soluble Au/DNA nanohybrid as the catalyst. The interactions between the gold nanoparticles, DNA, and water lead to high catalytic efficiency under mild reaction conditions. The wide substrate scope includes less‐basic aromatic amines, and this catalyst is recyclable.

2'-Aminoacetophenones undergo a C(sp)-H oxidation followed by intramolecular C-N bond formation by virtue of a simple electrochemical oxidation in the presence of n-BuNI, providing various isatins with moderate to good yields. The reaction intermediates were detected, and a radical-based pathway was proposed.