These data indicate that resveratrol might protect syncytiotrophoblast against TCA-induced inflammatory injury by upregulation of SIRT1 and downregulation of NF-κB and TNF-α. Resveratrol could be a potential therapeutic target for ICP.

The silica/titanium dioxide composite fiber membrane is prepared by electrospinning. Based on the shielding effect of rutile titanium dioxide on infrared rays, the fiber membrane has lower infrared transmittance and thermal conductivity.

Background To compare OCs(oral contraceptives) + metformin and OCs alone for metabolic effects in nonobese polycystic ovary syndrome (PCOS) patients. Methods The search was performed in PubMed, EMBASE, the Cochrane Library and http://clinicaltrials.gov for all published studies up to 30 April 2022 and was limited to English‐language articles. All randomized controlled trials (RCTs) comparing OCs + metformin and OCs alone for reproductive‐age women with PCOS were included. Data were processed using Revman 5.3 software. Results Of 396 studies identified, 14 RCTs were included for analysis comprising 707 women. OCs+metformin significantly modified fasting glucose (MD = −0.21 [95% confidence interval (CI) = −0.31, −0.12], p < .00001) and fasting insulin (MD = −2.54 [95%CI = −4.04, −1.04], p = .0009) at study completion compared with OCs alone in nonobese PCOS subjects. There was no statistic difference in the homoeostasis model assessment of insulin resistance (HOMA‐IR), high‐density lipoprotein (HDL), low‐density lipoprotein (LDL), total cholesterol or triglycerides at study end between the two groups. Conclusions Metformin, via its positive effects on insulin clearance, in combination with OCs, improved glucose metabolism and offered a good treatment alternative in nonobese women with PCOS.

A silica/cesium tungsten bronze composite fiber membrane with good near-infrared shielding performance is prepared by electrostatic spinning, and can be used for solar heat insulation.