In this work, we developed a ferroptosis self-catalyst PTAF, exhibiting self-catalyzed ferroptosis for enhanced cancer therapy. Briefly, synergistic actions of self-catalyzed ·OH accumulation and GPX4 indirect inactivation based on the...
In this study, we combined low pH and cathepsin B dual stimulus-triggered delivery carriers with the bioorthogonal reaction-activated prodrug to achieve regulated activation of prodrug. A workable method for precise...
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