China is a large agricultural country that has abundant biomass resource which can be generated biogas for heating and lighting. To improve biogas production efficiency of human excreta, which is a main kind of material in household biogas use, a laboratory-scale simulated experimental using self-designed constant temperature anaerobic fermentation equipment was conducted in our study. The results showed that increase of temperature can improve biogas generation efficiency of human excreta, and the other way is to mix the human excreta with other materials especially with the high C materials. Compare with the high costing of increase temperature, co-digestion with wheat straw has obvious advances: the crop straw can easily obtain and both wastes can be handled in the anaerobic fermentation process. The co-digestion developed in our study may be applicable to human excreta with other crop straws such as corn straw for biogas production.