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Background/Aim. The diagnosis of tumors of salivary glands relies heavily on radiological examination and biopsy of pathological tissue. The aim of this study was to investigate the sensitivity, specificity and accuracy of core needle biopsy in diagnosis of tumors of parotid and submandibular glands. Methods. This study was designed as a crosssectional clinical trial performed between May 2008 and Мay 2015 at the Department of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center Zemun, Belgrade, Serbia. The examinations included 200 patients among which 100 were diagnosed with tumors of parotid salivary glands and 100 with tumors of submandibular salivary glands. The core needle biopsy was undertaken in all cases where tumor was smaller than 2 cm, far from blood vessels and far from the deep layer of parotid gland. The histopathological analysis was performed to identify histological type of the lesion. Upon performing the surgical procedure and consequently the tumor tissue extirpation, tissue samples obtained were investigated for the definitive diagnosis. Results. The sensitivity of the procedure was 90.9% for parotid salivary gland and 74% for submandibular salivary gland, the specificity was 95.9% for parotid salivary gland and 93% for submandibular salivary gland and the accuracy was 94.7% for parotid salivary gland and 87% for submandibular salivary gland. Based on the histopathological findings of the salivary glands obtained using core needle biopsy of the tumor tissue, it was possible to differentiate between malignant and benign lesions. Conclusion. Current investigation points to the advantages and efficiency of core needle biopsy in diagnosis of tumors of parotid and submandibular salivary glands. Oroz A, et al. Vojnosanit Pregl 2019; 76(9): 921-928. nalaza biopsije šupljom iglom bilo je moguće diferencirati maligne od benignih lezija. Zaključak. Sprovedeno istraživanje ukazuje na prednost i efikasnost biopsije šupljom iglom u dijagnozi tumefakata doušne i podvilične pljuvačne žlezde.Ključne reči: biopsija tankom iglom; biopsija iglom; dijagnoza; histološke tehnike; parotidne žlezde, neoplazme; senzitivnost i specifičnost; submandibularne žlezde, neoplazme.

Cytologic and histologic grading were not identical in 34.6% of the imprints what points out the need to further definition of diagnostic criteria, especially for grade II of differentiation.

Introduction Angiomyolipomas represent neoplasms of mesenchymal origin, made up of abnormal thick-walled blood vessels, smooth spindle muscle cells, and mature adipose cells. The most common site of origin are kidneys, and other localizations are extremely rare. We represent a case of a spermatic cord angiomyolipoma misdiagnosed as incarcerated inguinoscrotal hernia, and to our prudence this is second described case of an angiomyolipoma localized in the spermatic cord. Case outline We present a case of a 63-year-old man presented with high fever and difficulty in walking due to pain and swelling in the right groin. According to the clinical examination and laboratory tests, presumptive diagnosis was incarcerated inguinoscrotal hernia, so the patient was immediately operated on. The exploration of the inguinal canal showed a timorous mass, 9 × 9 cm in size, with the origin from the spermatic cord, so radical inguinal orchiectomy was performed with the removal of the tumor mass. Histopathological and immunohistochemistry examination suggested angiomyolipoma of the spermatic cord. The postoperative course was uneventful. Conclusion Although rare, an angiomyolipoma of the spermatic cord must be included in the differential diagnosis of scrotal masses. Also, we advocate additional diagnostic procedures (ultrasound or computed tomography) for every inguinoscrotal mass before undertaking surgery, since a variety of different causes can be found. After definitive angiomyolipoma diagnosis is obtained, further investigation is needed, especially brain computed tomography due to possible tuberous sclerosis coexistence.

Penile tumors are rare neoplasms of the male urogenital tract and represent approximately 1% of all urogenital cancers in men. Squamous cell carcinoma is the most common histological type of these tumors, and is seen in about 95% of the cases. We report a case of a 66 years old male patient presented with large, neglected cancer of the penis, which grew about 6 months, but patient was not motivated for treatment until tumor began to bleed. Patient was operated and tumor was completely removed. The early postoperative course was uneventful and the patient was discharged from hospital Since penile cancers are rare entity, there are counted controversy about the best method of treatment. We believe that the individual approach to each patient relying on existing good clinical practice guidelines is currently the best therapeutic approach. ApstraktTumori penisa su najređi tumori urogenitalnog trakta kod muškaraca i čine manje od 1% svih tumora ove regije. Planocelularni karcinom je najčešći histološki tip ovih tumora i viđa se u oko 95% sluča-jeva. Prikazujemo slučaj pacijenta starosne dobi 66 godina, kod koga je dijagnostikovan veliki, zapušteni karcinom penisa koji je rastao 6 meseci, a pacijent nije bio motivisan da se javi na pregled sve do trenutka izraženog krvarenja iz tumorske promene. Pacijent je ubrzo operisan i tumor je u potpunosti odstranjen, a rani postoperativni tok je protekao uredno i pacijent je otpušten sa odeljenja. S obzirom da su karcinomi penisa redak entitet, javljaju se broje kontroverze po pitanju načina lečenja ovih promena. Mi smatramo da je individualni pristup svakom pacijentu uz oslanjanje na postojeće vodiče dobre kliničke prakse trenutno najbolji terapijski pristup.Ključne reči: karcinom penisa; planocelularni karcinom penisa Prikaz slučajaPrikazujemo slučaj pacijenta, starosne dobi 66 godina koji je primljen u našu ustanovu preko hitne hirurške ambulante zbog izraženog krvarenja iz velike tumorske promene na penisu. U momentu prijema pacijent je svestan, orijentisan, blede prebojenosti kože, kahetičan. Objektivni pregled trbuha bio je u granicama normale. Lokalnim pregledom urogenitalnog trakta konstatovana je velika egzulcerisana promena dimenzija 13 x 11 x 9 cm dominantno u regiji penisa, ali koja značajno prelazi njegove granice i zahvata i okolna tkiva, testisi nisu bili dostupni palpaciji (slika 1). Ingvinalni limfni čvorovi nisu bili uvećani. Pacijent je primetio promenu na glansu penisa 6 meseci pre nego što se javio lekaru, ali usled teških porodičnih problema i smrti bliskog člana porodice, pacijent nije bio motivisan da se javi lekaru. Dva dana pre nego što je primljen u našu ustanovu primetio je da promena krvari na dodir, a u nekoliko navrata je primetio i gnojavi iscedak iz kripti na skrotumu. U ličnoj anamnezi nije bilo značajnijih podataka. Po prijemu su urađene osovne laboratorijske analize koje su bile u granicama normale. Urađen je ultrazvučni pregled trbuha i male karlice, a potom i kompjuterizovana tomografija trbuha i male karlice koja je pokazala lezij...